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Found 5 clinical trials
Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex

This study will determine (1) whether baseline inhibitory activity in the primary motor cortex can predict motor learning ability in individuals with cerebellar degeneration, and (2) whether

  • 04 Oct, 2022
  • 1 location
Training in Ataxia - Individuals With Degenerative Cerebellar Diseases

Balance and aerobic training show promise as treatments for degenerative cerebellar diseases, but the neural effects of both training methods are unknown. The goal of this project is to evaluate how each training method impacts the brain, and particularly, the degenerating cerebellum. Various neuroimaging techniques will be used to accomplish …

  • 24 Mar, 2022
  • 1 location
Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases

This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a peripheral blood stem cell transplant works in treating patients with autoimmune neurologic disease that did not respond to previous therapy. In autoimmune neurological diseases, the patient's own immune …

antithymocyte globulin
gait ataxia
  • 11 Jul, 2022
  • 3 locations
Investigating Cerebellar Inhibition and Its Clinical Significance in Parkinsonian Tremor and Intention Tremor

tremor is usually found in the patients with cerebellar degeneration, which is also relevant to the CDTC circuit dysfunction. We expect that the clinical significance of CBI and the mediated pathway of

  • 04 Oct, 2022
  • 1 location
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy

The purpose of the study is to systematically characterize the clinical course of the progressive neuropathy and optic atrophy observe in pediatric and adult patients with biallelic mutations in the solute carrier family 25 member 46 (SLC25A46) gene.

  • 25 Jan, 2022
  • 1 location