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Found 19 clinical trials
Target Attainment of Cefuroxim

other cephalosporins, time-dependent killing. The pharmacodynamic target can therefore be best described as the percentage of the dosing interval that the serum concentration remains above the minimum

  • 0 views
  • 27 Apr, 2022
  • 1 location
Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections (TANGOKIDS)

A single dose infusion of Vabomere (meropenem-vaborbactam) is being tested for dose-finding, pharmacokinetics, safety, and tolerability in pediatric subjects from birth to less than 18 years of age with serious bacterial infections

renal function
absolute neutrophil count
antibiotics
antibiotic therapy
  • 5 views
  • 26 Jan, 2022
  • 5 locations
Antimicrobial Prophylaxis in Patients Who Underwent a Transurethral Resection of Bladder (TURB)

Antimicrobial prophylaxis in urological procedures is aimed to reduce the risk of local and systemic postoperative infections such as urinary tract infection or surgical site infection. It should be recommended only when the potential benefit exceeds the anticipated risks and costs. However, a wide variation in the use of periprocedural …

TURB
antimicrobials
antibiotics
trometamol
antibiotic therapy
  • 9 views
  • 23 Jan, 2021
  • 1 location
Acquisition of Resistant Enterobacteria During Oral Drug Challenge for Betalactams in Children

Direct drug provocation testing, without prior skin or in vitro testing, is the reference standard for confirming the diagnosis of drug hypersensitivity reactions in children reporting mild and delayed-onset reactions. However, optimal protocol(s) have not been standardized. Although a 2-days' provocation testing protocol is effective, increasing its duration (up to …

  • 0 views
  • 27 May, 2021
  • 1 location
Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia

This study is based on the hypothesis that the pharmacokinetics of antibiotics in children is different from adults. Cephalosporins and macrolide antibiotics are the common drugs for children

chest pain
fever
antibiotics
purulent sputum
x-rays
  • 0 views
  • 21 Jan, 2021
Clinical Comparison of Treatment Strategies in AmpC Beta-lactamase Producing Enterobacterales in a Swiss Tertiary Care Hospital (AmpCstratBasel)

This study is to investigate the recent epidemiological trends and the treatment outcome in terms of the length of hospital stay, the relevant renal and neurological side effects, risk factors for developing these side effects, the selection of more resistant pathogens under therapy as well as the incidence of Clostridium …

  • 0 views
  • 23 Mar, 2022
  • 1 location
Treating Non-typhoidal Salmonella Bloodstream Infections in Children Under Five in DR Congo: a Cohort Study

With this study the researchers aim to provide observational data on the treatment efficacy of currently used antibiotic treatment regimens for NTS BSI in hospital-admitted children. The study is an observational cohort study where the antibiotic treatments used and treatment outcomes in the St. Luc general referral hospital in Kisantu …

  • 0 views
  • 07 Sep, 2021
  • 1 location
Research of the Consequences on the Digestive Tract Following the Proposed Treatments for a Urinary Infection in Children

foreground. It remains active on the majority of E-ESBL strains. Some risk factors for E-ESBL emergence are known: recent antibiotic therapy (particularly quinolones and cephalosporins third generation

antibiotics
antibiotic therapy
beta lactamase
quinolones
amikacin
  • 60 views
  • 26 Nov, 2021
  • 42 locations
Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia

This study aims to assess whether ertapenem as an empiric treatment of third-generation-cephalosporin resistant Enterobacteriaceae (3GCRE) bacteremia is non-inferior to other carbapenems in term of 30-day mortality.

bacteremia
carbapenem
cephalosporins
  • 30 views
  • 02 May, 2022
  • 1 location