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Found 23 clinical trials
Early Sleep Apnea Treatment in Stroke (eSATIS)

Investigating the interrelation of stroke and sleep-disordered breathing (SDB) is of major importance. First because of the high occurrence rate of stroke and the fact that it is a frequent cause of long-term disability in adulthood. Second because SDB (obstructive, central and mixed forms) affects more than 50% of stroke …

diffusion weighted imaging
ischemic stroke
arterial stiffness
acute stroke
sleep-disordered breathing
  • 24 views
  • 22 Jan, 2022
  • 5 locations
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment (CSA)

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given

Accepts healthy volunteers
apnea-hypopnea index
central sleep apnea
heart failure
opioid
  • 0 views
  • 23 Mar, 2022
  • 1 location
Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure. (HO2F)

The aims of this study are to 1) determine the optimal levels of O2 flow which prevent nocturnal O2 desaturation while minimizing periods of hyperoxia during the course of nocturnal oxygen therapy (NOXT) in heart failure patients with reduced ejection fraction (HFrEF) patients with CSA/CSR; 2) document whether within-patient EO2F …

cheyne-stokes respiration
ejection fraction
heart disease
central sleep apnea
heart failure
  • 11 views
  • 25 Apr, 2022
  • 2 locations
Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude

Sleep at altitude is often poor. The purpose of this study is to evaluate the effects of a single dose of the opioid antagonist, naltrexone, on sleep quality and periodic breathing after rapid ascent to ~3800m altitude.

Accepts healthy volunteers
  • 0 views
  • 14 May, 2022
  • 1 location
Pathophysiological Study of CSA in Adults With pLVEF

Sleep apnea is classically divided into obstructive and central apnea, according to the persistence or otherwise of respiratory movements and the existence or not of pharyngeal collapse during

polysomnography
collapse
snoring
heart failure
obstructive sleep apnea
  • 0 views
  • 29 Mar, 2021
  • 1 location
Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome

-hypopnea index (CAHI) for infants with Prader-Willi Syndrome. Despite the vast amount of research investigating the cause of central sleep apnea, there remain gaps in knowledge, lending to further

behavioral problems
sleep disordered breathing
apnea-hypopnea index
sleep-disordered breathing
impaired attention
  • 24 views
  • 24 Mar, 2022
  • 1 location
Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents

The research study is being done to test heated humidified high-flow air (HHF), as a treatment for OSA.

  • 0 views
  • 16 May, 2022
  • 1 location
ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea. (AMEND)

Obstructive sleep apnea (OSA), central sleep apnea (CSA) and heart failure (HF) are states of metabolic demand and sympathetic nervous system (SNS) activation. In patients with sleep apnea and

ejection fraction
bradley
medical therapy
continuous positive airway pressure
sleep disorder
  • 48 views
  • 24 May, 2022
  • 1 location
Brainstem Dysfunction Involvement in the Pathogenesis of Pierre Robin Sequence (DYSROBIN)

pathogenesis of PRS. The purpose of the study is to achieve a complete evaluation of BSD to specify its role in the pathogenesis of PRS. The primary objective is to compare central apnea index

  • 5 views
  • 04 Mar, 2022
  • 1 location
Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension

There is evidence for a high prevalence of Sleep Disorder Breathing (SDB) in patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH). Central Sleep Apnea, Cheyne-Stokes Breathing and

riociguat
sleep disorder
obstructive sleep apnea
central sleep apnea, cheyne-stokes breathing
apnea
  • 3 views
  • 23 Apr, 2022
  • 1 location