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Found 41 clinical trials
Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?

Vulvar Pain Assessment Questionnaire (VPAQ), the Female Sexual Functioning Index, the Pain Catastrophizing Scale, the Depression Anxiety Stress Scales and the Central Sensitization Inventory. Three

  • 12 views
  • 10 Oct, 2021
  • 1 location
Which Exercise for Low Back Pain? Predicting Response to Exercise for Patients With Low Back Pain

Exercise therapy is the most recommended treatment for chronic low back pain. There is a wide range of exercises available and research studies have shown that no exercise is superior to another. The problem is that the effects of exercise in reducing pain and disability are small to moderate. Researchers …

  • 11 views
  • 20 Apr, 2022
  • 1 location
Rehabilitation for Whiplash Associated Disorders

Individuals (n=180) with subacute (<1 month, >3 months) WAD grade I and II with medium to high-risk symptoms of working age will be randomized into three groups with block randomization in a prospective, assessor-blinded randomized controlled trial. Two primary intervention groups (A and B) will receive manual therapy (MT) in …

  • 0 views
  • 04 Oct, 2022
  • 1 location
The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy (B²EARS)

This study aims to assess the effectiveness of perioperative pain neuroscience education (PPNE) in patients who are at risk for unfavorable outcome following surgery for lumbar radiculopathy. Although most of these surgeries are successful, 23-28% of patients report chronic pain and disability following surgery. Many preoperative factors are associated with …

  • 0 views
  • 04 Oct, 2022
  • 3 locations
Duloxetine RCT on Postop TKA Outcomes

The aim of this study is to determine if duloxetine is associated with differences in post-operative pain, patient-reported outcome measures, and opioid consumption in patients undergoing primary total knee arthroplasty compared to patients who do not receive the medication. If so, duloxetine has the potential to become widely incorporated into …

Accepts healthy volunteers
  • 0 views
  • 26 Nov, 2021
  • 1 location
Well-Being After Breast Cancer Surgery (WB ABCs)

The purpose of this study is to compare the benefits of skills training and health education interventions designed specifically to increase the well-being of people with persistent pain after breast surgery for lobular carcinoma in situ (LCIS), ductal carcinoma in situ (DCIS), or invasive breast cancer, and to examine the …

  • 0 views
  • 07 Jul, 2022
  • 2 locations
Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or

tramadol
opioid
tension headache
hydromorphone
oxycodone
  • 38 views
  • 25 Mar, 2022
  • 1 location
Pain, Sleep and Gut Microbiota

peripheral sensitization of nociceptors, and the susceptibility to develop central sensitization of pain pathways. To assess susceptibility to peripheral sensitization, a solution of capsaicin (the active

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Analgesic Effect of Intraoperative Intravenous S-Ketamine After Total Knee Arthroplasty Surgery:A Randomized Controlled Clinical Trial

-methyl-d-aspartate (NMDA) receptor activation and attenuates central sensitization associated with hyperalgesia, opioid tolerance.Therefore, the primary aim of this trial was to investigate whether s

  • 0 views
  • 28 Oct, 2022
  • 1 location
Dry Needling Effects on Cortical Excitability

), specifically in patients who have developed central sensitization (CS). Therefore, the primary purpose of this study is to examine the immediate effects of a single session of DN on cortical excitability and

low back pain
dry needling
back pain
  • 0 views
  • 04 Oct, 2022
  • 1 location