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Found 10 clinical trials
Switch to Oral Antibiotics in Gram-negative Bacteremia (SOAB)

, central nervous system infection, terminal illness with expected survival less than 14 days, absolute neutrophil count less than 1,000/ml and hematopoietic or solid organ transplantation within the

  • 77 views
  • 18 Apr, 2022
  • 7 locations
Ceftriaxone as Home IV for Staph Infections

Patients who are admitted to hospital with serious infections, such as those in bone, joints or spine, require a long course of intravenous (IV) antibiotics. After an initial treatment course in hospital or through a dedicated outpatient antibiotic program many patients can complete their treatment course at home. Such infections …

prosthetic joint infection
antibiotics
epidural abscess
cloxacillin
joint infection
  • 42 views
  • 16 Feb, 2022
  • 2 locations
Developing Metagenomic Approaches to Identify the Causes of Pediatric Infectious Diseases

detection range. Metagenome next generation sequencing (mNGS) has been applied to the diagnosis of central nervous system infection, lower respiratory tract infection and sepsis, which showed high positive

  • 0 views
  • 02 Mar, 2022
  • 1 location
Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

intravenously administered fosfomycin, including patients with osteomyelitis, complicated urinary tract infection, nosocomial lower respiratory tract infection, bacterial meningitis/central nervous system

soft tissue infection
bacterial infections
nosocomial infections
osteomyelitis
bacteraemia
  • 644 views
  • 27 Jan, 2022
  • 24 locations
National Study on Listeriosis and Listeria (MONALISA)

Listeriosis is a foodborne infection responsible for severe disease. Three main forms are described: septicaemia, central nervous system infections and maternal-fetal infections. Available data on the disease, are mostly retrospective and do not provide an accurate picture of the clinical / biological / genetic risk factors for the disease, nor …

prenatal
  • 82 views
  • 15 Jul, 2022
  • 1 location
Central Nervous System Infections in Denmark (DASGIB)

The Danish Study Group of Infections of the Brain is a collaboration between all departments of infectious diseases in Denmark. The investigators aim to monitor epidemiological trends in central nervous system (CNS) infections by a prospective registration of clinical characteristics and outcome of all adult (>17 years of age) patients …

syphilis
serological tests
antibiotics
meningitis
blood culture
  • 345 views
  • 26 Feb, 2022
  • 8 locations
Central Nervous System Disorders Following Hematopoietic Stem Cell Transplantation

All patients undergoing allogeneic or autologous HSCT at the participating centres will be observed. Once a diagnosis of CNS disorder is made, additional data will be reported for these patients. We will identify clinical and diagnostic characteristics such as cerebrospinal fluid (CSF) and neuroimaging patterns, risk factors, response to treatment …

antifungal
cell transplantation
colony stimulating factor
  • 0 views
  • 20 Jun, 2022
  • 17 locations
Clinical Value of Metagenomic Sequencing in Neonatal Sepsis

This study aimed to enroll 2000 neonatal patients with suspected sepsis or clinical diagnosed sepsis. These patients will undergo both conventional methods and metagenomics sequencing to detect the pathogenic microorganisms of sepsis. The purpose of this study was to assess the clinical value of metagenomics sequencing for the diagnosis and …

  • 0 views
  • 03 Jul, 2022
  • 1 location
Serum Levels of Adipocytokines in Children With Febrile Seizures: A Cross-Sectional Study at Sohag University Hospital

accompanied by a fever (≥38°C) without central nervous system infection. FS is classified into simple febrile seizure (SFS) and complex febrile seizure (CFS). SFS accounts for 70-75% of FS cases and is

Accepts healthy volunteers
  • 0 views
  • 23 Sep, 2022
  • 1 location
Determination of COVID-19 Related Virus in Central Nervous System

Coronavirus disease 2019 (COVID-19) is a highly infectious pandemic disease caused by SARS-CoV-2 virus. Central Nervous System (CNS) complications associated with COVID-19 might be secondary sequelae due to exuberant systemic innate-mediated hyper-inflammation, which may impair neurovascular endothelial function, disrupt blood brain barrier (BBB), activates CNS innate immune signaling pathways, and …

  • 0 views
  • 12 Mar, 2021
  • 1 location