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Found 907 clinical trials
Featured trial
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

) transplant procedure. cGVHD is a common complication of stem cell transplantation, resulting from the donor cells attacking the transplant recipient's tissues. In oral cGVHD, the tissues in the mouth are

graft versus host disease
graft-versus-host disease
  • 164 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the

sickle cell disease
cell transplantation
stroke
red blood cell disorder
  • 83 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Single-Cohort, Phase 2 Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft Versus-Host Disease

A Single-Cohort, Phase 2 Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft Versus-Host Disease

bone marrow transplant
transplant conditioning
stem cell transplant
stem cell transplantation
nutritional supplement
  • 322 views
  • 08 Dec, 2020
  • 1 location
Featured trial
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

people who need stem cell transplants. Eligibility: Individuals who are scheduled to have a stem cell transplant. Design:

anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
  • 80 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

cell transplant with fewer complications. Objectives: To evaluate a new method of stem cell transplantation that may reduce the possibly of severe side effects

anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
  • 194 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Haplo-identical Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

inserted in the neck or chest Medicines for side effects Chemotherapy over 8 days and radiation 1 time Stem cell transplant over 4 hours Up to 6 months after

anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
  • 75 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of blood

anemia studies
aplastic anemia
myelodysplastic syndrome (mds)
myelodysplastic syndromes
  • 57 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

the patient s healthy tissues. The average hospital stay after stem cell transplantation is 3 to 4 weeks. Patients return for frequent follow-up visits for the first 2 to 4 months after

anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
  • 54 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS)

  • 312 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Randomized Trial of Sirolimus (Rapamune) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Background: People with severe aplastic anemia (SAA) do not make enough red and white blood cells, and/or platelets. Their body's immune system stops the bone marrow from making these cells. The treatment cyclosporine leads to better blood counts. But when this treatment is stopped, the disease may return in 1 …

anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
myelodysplastic syndrome (mds)
  • 75 views
  • 22 Dec, 2020
  • 1 location