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Found 65 clinical trials
Effect of 35624 Alflorex in Functional Gastrointestinal Disorders (FGIDs) in Children.

The aim of this study is to evaluate the effect of supplementation with Bifidobacterium longum 35624 Alflorex on frequency and severity of symptoms of abdominal pain using the Irritable Bowel Syndrome Gastrointestinal Symptom Rating Scale (IBS-GSRS) and validated Numeric Pain Rating Scale (NRS-II) in children with Functional Gastrointestinal Disorders (FGIDs).

  • 12 Sep, 2021
  • 1 location
Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

The purpose of this study is to examine the feasibility of using a trans-nasal IPD probe as a measurement tool for gut permeability

small intestine
  • 01 Aug, 2021
Laparoscopic Ischemic Conditioning Prior to Esophagectomy (ISCON)

This is a two center phase II prospective single-arm safety and feasibility trial for 20 patients with resectable esophageal carcinoma with an increased risk for anastomotic leakage, as based upon UCS and NASCET calcification scores on pre-op CT-scan. In these patients, laparoscopic ischemic conditioning is performed 12-18 days before an …

indocyanine green
ct scan
squamous cell carcinoma
esophageal carcinoma
  • 22 Mar, 2022
  • 2 locations
RAMIE Versus MIE for Resectable Esophageal Cancer, a Randomized Controlled Trial (ROBOT-2 Trial). (ROBOT-2)

BACKGROUND: For patients with esophageal cancer, radical esophagectomy with 2-field lymphadenectomy is the cornerstone of the multimodality treatment with curative intent. Both, conventional minimally invasive esophagectomy (MIE) and robot assisted minimally invasive esophagectomy (RAMIE) were shown to be superior compared to open transthoracic esophagectomy considering postoperative complications. However, no randomized …

  • 23 May, 2022
  • 1 location
Evaluation of Complete microscopicE Resection Margin (R0) and Lymph Node Involvement After Standard Pancreatosplenectomy (SPS) Versus Radical Anterograde Modular Pancreatosplenectomy (REMIND-01)

Resection with negative margins (R0) followed by adjuvant chemotherapy is today the standard of care and the only chance of cure for patients with pancreatic ductal adenocarcinoma (PDA). Incomplete microscopic resection margin (R1) after pancreatic resection has been reported to occur in 17 to >80% of cases depending on the …

breast ductal carcinoma
cancer chemotherapy
  • 27 Feb, 2022
  • 1 location
Confocal Laser Endomicroscopy to Determine Influence of Food Antigens on Mucosal Integrity

Irritable bowel syndrome (IBS) is mainly associated with food intolerance and presents a particular challenge in gastrointestinal practice. The clinical symptoms are often associated by patients with the consumption of certain foods. This leads to strict elimination diets, and often without identification of the triggering food. In particular, the avoidance …

  • 29 Sep, 2021
  • 1 location
Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis

Prospective double-blinded placebo-controlled study, among adult patients suffering from moderate-to-severe atopic dermatitis (AD), insufficiently responsive to topical and systemic treatment. In the first group all patients will receive 4 fecal microbial transplantations (FMTs) from healthy donors each 2 weeks apart. In the second group all patients will receive 4 placebo …

topical corticosteroid
  • 05 Jun, 2022
  • 2 locations
Diabetes and Osteopathic Manipulative Medicine (OMM)

Our research team is proposing a study to investigate the effects of osteopathic manipulative treatment on the blood sugar levels of persons with Type 2 diabetes. The goal of this study is to determine if osteopathic manipulative treatment (OMT) can improve the blood sugar levels of individuals with Type 2 …

  • 11 May, 2022
  • 2 locations
Physical Fitness in Celiac Disease Patients - the Effect of a Gluten Free Diet

Evaluating the effect of Celiac disease (CD) and gluten free diet (GFD) on physical fitness parameters among CD subjects. The CD subjects will be compared to healthy controls.

  • 25 Jan, 2021
  • 1 location
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis

Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.

endoscopic ultrasound
  • 24 Jan, 2021
  • 1 location