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Found 26 clinical trials
Ceftriaxone as Home IV for Staph Infections

there are three antibiotic options used routinely. A fourth antibiotic, ceftriaxone, is a promising alternative; it is also effective against Staphylococci, and is more convenient, less costly and

cloxacillin
staphylococcus aureus
methicillin
cefazolin
prosthetic joint infection
  • 42 views
  • 16 Feb, 2022
  • 2 locations
Ceftriaxone to PRevent pneumOnia and inflammatTion aftEr Cardiac arresT (PROTECT)

Randomized-controlled trial and microbiome assessment to understand the risk-to-benefit ratio of prophylactic antibiotics (Ceftriaxone) vs placebo in patients with pneumonia and inflammation

antibiotics
pneumonia
ceftriaxone
  • 0 views
  • 18 Sep, 2021
  • 1 location
Cefuroxime vs Ceftriaxone for SSI Prevention in Neurosurgery

second generation Cephalosporin) to Ceftriaxone (a third generation Cephalosporin) in neurosurgical procedures will provide more knowledge on the efficacy of Cefuroxime as antibiotics prophylaxis.

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
  • 1 location
To Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson's Disease Dementia

This is a randomized, double blinded, placebo-controlled Phase II study to investigate the efficacy and safety of ceftriaxone in patients with mild to moderate Parkinson's disease dementia (PDD

  • 3 views
  • 21 Apr, 2022
  • 4 locations
PROPER Trial of Pain and Inflammation After Knee Arthroscopy (PROPER)

The purpose of this study is to determine if ceftriaxone administered postoperatively via intravenous injection reduces postoperative visual analog scale (VAS) pain scores and narcotic

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units (Pop-PK/PD)

result, serum concentrations show important interpatient variations with the risk of being subtherapeutic or toxic. Recent studies with temocillin, ceftriaxone, or meropenem confirm this for patients in

renal function
pulmonary infection
antibiotics
antibiotic therapy
ceftriaxone
  • 30 views
  • 04 Jun, 2022
  • 1 location
Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition

This study to investigate whether empiric use of an antibiotic with greater antimicrobial sensitivity (ceftriaxone) than standard-of-care (ampicillin plus gentamicin) will reduce mortality among

  • 0 views
  • 08 Oct, 2021
  • 1 location
Antimicrobial Treatment in Patients With Ventilator-associated Tracheobronchitis

Antimicrobial treatment could be beneficial in patients with ventilator-associated tracheobronchitis (VAT). The hypothesis of this study is that antibiotic treatment for VAT (3 or 7 days), compared with no antibiotic treatment, would reduce the incidence of transition from VAT to ventilator-associated pneumonia (VAP).

tracheobronchitis
imipenem
pneumonia
antibiotics
invasive mechanical ventilation
  • 0 views
  • 24 Jan, 2021
  • 1 location
Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Secondary infections remain a major cause of mortality in critically ill patients, mainly because of high prevalence of multidrug-resistant microorganisms. Therefore strategies aimed to reduce the incidence of ventilator-associated pneumoniae (VAP) and bloodstream infections are of utmost important. There is robust data on selective digestive decontamination (SDD) efficacy in reduction …

vancomycin
pneumonia
antibiotics
oropharyngeal
assisted ventilation
  • 0 views
  • 19 Jun, 2021
  • 1 location
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (PNLABXPART2)

This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy. The select patient population will be those patients deemed to be at a moderately increased risk of postoperative infectious complications. These higher risk …

antibiotic prophylaxis
nephrostomy
urine culture
percutaneous nephrolithotomy
nitrofurantoin
  • 35 views
  • 24 Feb, 2022
  • 1 location