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Found 8 clinical trials
Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR)

This study will assess the pharmacokinetics, safety, and tolerability of single and multiple doses of intravenous ceftazidime-avibactam in hospitalized infants and neonates from 26 weeks

  • 152 views
  • 10 Aug, 2022
  • 22 locations
Study to Optimize the Use of New Antibiotics (NEW_SAFE)

patients who have received either empirical or targeted treatment with ceftaroline, tedizolid, dalbavancin, ceftazidime-avibactam, ceftolozane-tazobactam and isavuconazole from January 2016 to December

antibiotic therapy
antimicrobials
tedizolid
isavuconazole
bacteremia
  • 3 views
  • 16 Feb, 2022
  • 13 locations
Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae Infections (AVI-ICU)

> Colistin-based combination regimens have been the mainstay for treating CRE-related infections. Ceftazidime-avibactam is a beta-lactamase inhibitor combination, a novel antibiotic, which recently showed a

  • 0 views
  • 14 Jul, 2022
  • 1 location
Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP)

This is a prospective, single arm, open-label, multi-center clinical study evaluating the effectiveness and safety of CAZ-AVI in participants with HAP (including VAP), who have initiated treatment with CAZ-AVI in an inpatient hospital setting. The duration of antibiotic treatment with the CAZ-AVI is 7-14 days. Participants must receive intravenously (IV) …

  • 2 views
  • 10 Aug, 2022
  • 28 locations
Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections

This is an observation study comparing prospective use of Imipenem/Cilastatin/Relebactam (IMI/REL) to retrospective data using Meropenem/Vabobactam (MVB)and Ceftazidime/Avibactam CZA) in

ceftazidime
antibiotics
imipenem
cilastatin
bacteremia
  • 8 views
  • 12 Jul, 2022
  • 1 location
ZAVI APD ELF Protocol v2.2

CAZ/AVI is a new antibiotic drug that is meant to be used for various indications including cIAI and nosocomial pneumonia. To date, limited data exists on PK of CAZ/AVI in patients undergoing peritoneal dialysis as well as on penetration of CAZ/AVI in ELF of critically ill patients. The present study …

pneumonia
antibiotic therapy
antibiotics
nosocomial pneumonia
dialysis
  • 48 views
  • 28 Feb, 2022
  • 1 location
Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

treatment with Ceftazidime-Avibactam will be enrolled. Blood samples at 0, 2, 4, 6, and 8 h after the first time and the steady state(5 times) of administration will be collected to detect plasma

severe sepsis
  • 0 views
  • 01 Jul, 2022
  • 1 location
Use of New Antibiotics in Sweden

Antibiotic resistance is a growing global health problem of great concern, especially multidrug-resistant Gram-negative bacteria. In recent years some new antibiotics targeting these bacteria have been developed. The aim of this study is to investigate how these new antibiotics are used in Sweden. Information will be collected on patients, types …

  • 0 views
  • 23 Mar, 2022
  • 7 locations