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Found 123 clinical trials
Characterization of Arrhythmia Substrate to Ablate Persistent Atrial Fibrillation (COAST-AF RCT)

A multicentre, parallel group, two arm, single-blinded randomized clinical trial, assessing the efficacy of a patient-tailored catheter ablation (CA) strategy guided by atrial scar mapping in

persistent atrial fibrillation
fibrillation
12 lead ECG
arrhythmia
electrocardiogram
  • 28 views
  • 14 Feb, 2022
  • 13 locations
N-Acetylcysteine Protection Against Radiation Induced Cellular Damage

Catheter ablation procedures (CAPs) are first line treatment for a great variety of cardiac arrhythmias. CAPs require X-Ray imaging; consequently, CAPs cause ionizing radiation (IR) exposure for

  • 0 views
  • 15 Feb, 2021
  • 1 location
Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation (CHANGE-AFIB)

While there are several completed clinical trials that address treatment strategy in patients with symptomatic and recurrent AF, there are no randomized clinical trials that address treatment for first-detected AF. In usual care, these patients are started on an atrioventricular nodal blocking agent (beta-blocker or non-dihydropyridine calcium channel blocker) along …

calcium
antiarrhythmic drug
stroke
fibrillation
dronedarone
  • 0 views
  • 01 Jul, 2022
  • 10 locations
Impact of Pacing Output and Cycle Length on QRS Morphology

Current recommendations for pacemapping are based on expert opinion and animals models. Present study sought to evaluate the influence of different parameters of pacemapping on QRS morphology. Pacemapping is performed with different cycle length (fixed burst vs. coupling interval) and stimulation output (maximum output vs. threshold) and resulting QRS complexes …

  • 0 views
  • 16 Nov, 2021
  • 1 location
Comparison Between Upgraded '2C3L' vs. PVI Approach for Catheter Ablation of Persistent Atrial Fibrillation

Catheter ablation has emerged as an important treatment option for patients with symptomatic atrial fibrillation (AF). Pulmonary vein antral isolation (PVI) is now considered as the cornerstone

persistent atrial fibrillation
ejection fraction
fibrillation
aspirin
arrhythmia
  • 0 views
  • 08 Jan, 2022
  • 1 location
Randomized Trial: High Power Short Duration Versus Ablation Index

The single procedure success rates of durable pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) varies between 80 and 90 %. This prospective, randomized study investigated the efficacy of pulmonary vein isolation with RF-energy following the CLOSE protocol with standard energy application (30 Watts) versus PVI with RF-energy with …

Accepts healthy volunteers
  • 0 views
  • 15 Mar, 2022
  • 1 location
Zero Fluoroscopy Voltage Guided vs. Linear CTI Ablation (ZERO MAGIC)

Catheter ablation of the cavo-tricuspid isthmus (CTI) is the curative first-line therapy for typical atrial flutter. Currently, two approaches are used in clinical practice. In contrast to the

  • 0 views
  • 25 May, 2022
  • 1 location
Post-Ablation Pericarditis Reduction Study

There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques. The hypothesis is that an empiric pre and post AF ablation treatment protocol with colchicine may reduce the incidence and symptom severity of post-AF ablation related …

fibrillation
hmg-coa reductase inhibitors
  • 0 views
  • 08 Jun, 2021
  • 1 location
Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial

The purpose for this study is to determine whether left posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) is effective as ablation strategy for persistent atrial fibrillation (AF).

catheter ablation
antiarrhythmic drug
persistent atrial fibrillation
fibrillation
pulmonary vein isolation
  • 0 views
  • 18 Sep, 2021
  • 1 location
Catheter Ablation in Symptomatic Atrial Fibrillation

This is a double blinded randomised placebo-controlled trial comparing the effects of catheter ablation (Cryoablation) versus a placebo procedure on atrial fibrillation burden, symptoms and

catheter ablation
antiarrhythmic drug
persistent atrial fibrillation
fibrillation
pulmonary vein isolation
  • 77 views
  • 27 Feb, 2022
  • 3 locations