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Found 11 clinical trials
featured
Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.

excessive daytime sleepiness
cataplexy
sodium oxybate
stimulant
multiple sleep latency test
  • 80 views
  • 10 Jul, 2018
  • 53 locations
featured
A Study to Evaluate Safety, and Efficacy of SUVN-G3031 in Patients With Narcolepsy With and Without Cataplexy (SUVN-G3031)

This study is of an investigational drug called SUVN-G3031 as a possible treatment for narcolepsy with cataplexy or narcolepsy without cataplexy. The main purpose of this study is to learn

cataplexy
na-1
sleep latency test
multiple sleep latency test
experimental drug
  • 204 views
  • 23 Nov, 2020
  • 1 location
featured
Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether Sodium Oxybate is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.  

excessive daytime sleepiness
sodium oxybate
cataplexy
stimulant
  • 217 views
  • 22 Feb, 2019
  • 1 location
A Study to Evaluate Safety and Efficacy of SUVN-G3031 in Patients With Narcolepsy With and Without Cataplexy

This study is of an investigational drug called SUVN-G3031 as a possible treatment for narcolepsy with cataplexy or narcolepsy without cataplexy. The main purpose of this study is to learn how

cataplexy
experimental drug
body mass index
urine drug screen
na-1
  • 1226 views
  • 19 Apr, 2021
  • 49 locations
Awareness and Self-Compassion Enhancing Narcolepsy Treatment

The overall goal of this research is to test the effectiveness of a mindfulness-based intervention (MBI) for improving health-related quality of life as a complementary practice to standard care for narcolepsy. This study is a feasibility trial in which 60 adults with narcolepsy will be randomized to receive either a …

multiple sleep latency test
psychological distress
depression
  • 156 views
  • 22 Aug, 2021
  • 1 location
Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia

For diseases that cause excessive daytime sleepiness (such as narcolepsy and idiopathic hypersomnia), there are several medications that can be used to treat sleepiness. However, it can be difficult to decide which medication to use for a particular individual for several reasons: 1) there are very few studies that directly …

sleep disorders
cataplexy
amphetamine
narcolepsy
sleepiness
  • 416 views
  • 05 Jul, 2021
  • 1 location
Clarithromycin Mechanisms in Hypersomnia Syndromes

The purpose of this study is to evaluate a medication called clarithromycin for treating sleepiness in two related conditions, narcolepsy without cataplexy and idiopathic hypersomnia. Studies

sleep disorders
cataplexy
clarithromycin
multiple sleep latency test
narcolepsy
  • 67 views
  • 09 Jul, 2021
  • 1 location
An Open Label Study of FT218 in Subjects With Narcolepsy

twice-nightly immediate release sodium oxybate to once-nightly FT218 for the Treatment of Excessive Daytime Sleepiness and Cataplexy in Subjects with Narcolepsy

excessive daytime sleepiness
cataplexy
sodium oxybate
sleepiness
somnolence
  • 258 views
  • 15 Aug, 2021
  • 5 locations
Microglial Activation in Narcolepsy Type 1 and Kleine-Levin Syndrome: Positron Emission Tomography (PET) Study in [18F] DPA-714

currently only symptomatic, targeting hypersomnolence and cataplexy. To prevent the destruction of Hcrt neurons, immunomodulatory agents have been tested, with varying efficacy, probably due to varying

  • 105 views
  • 25 Jan, 2021
  • 1 location