Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 66 clinical trials
Individualized Physical Activity and Carotid Plaque Instability

Intraplaque hemorrhage (IPH) is one of the main features of the carotid plaque instability's and predictor of ischemic stroke. Benefits (on the basis on benefit/risk ratio) of the carotid endarterectomy remain unclear for stroke asymptomatic patients; thus, more and more patients with important stenosis (i.e. over 60%) detected are not …

endarterectomy
stroke
stenosis
MRI
atherosclerosis
  • 0 views
  • 23 Jan, 2021
  • 1 location
PET Detection of CCR2 in Human Atherosclerosis

: Use of novel radio-pharmaceutical 64CUDOTA-ECL1i to evaluate arterial atherosclrosis

diabetes
atherosclerosis
  • 0 views
  • 25 Jan, 2021
Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound

This is an open-label, non-randomized study conducted at Thomas Jefferson University comparing pressure-gradient estimates (obtained between a carotid plaque and the carotid artery) to imaging and histology markers of plaque vulnerability. There is an inverse relationship between the subharmonic signal magnitude from contrast-enhanced ultrasound microbubbles and ambient pressure. This pressure …

  • 0 views
  • 26 Jan, 2021
  • 1 location
PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis

To demonstrate feasibility of imaging Cu[64]-25%-CANF-Comb uptake in the atherosclerosis of the carotid artery of patients for whom carotid artery endarterectomy surgery is planned in comparison to the carotid artery for which intervention is not planned.

endarterectomy
natriuretic peptide
atherosclerosis
positron emission tomography
  • 35 views
  • 16 Jun, 2021
  • 1 location
Evaluation of Cerebrovascular Events in Patients With Occlusive Carotid Artery Disorders

As of today, no suitable multiparametric predictive method is available to properly estimate stroke risk in patients with carotid artery stenosis. Carotid artery stenosis is one of the proven risk factors of stroke incidence, but the indication of its intervention is merely the grade of stenosis itself. The current international …

carotid artery stenosis
stroke
stenosis
angiography
endarterectomy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization

Stroke is the second leading cause of death in the Western world and the leading cause of major lifelong disability. About 15% of strokes are secondary to thrombosis or embolization of an unstable atheromatous carotid plaque. In these symptomatic patients, the degree of carotid stenosis is correlated with the risk …

carotid artery stenosis
preventive surgery
stroke
stenosis
endarterectomy
  • 0 views
  • 25 Jan, 2021
Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)

Multicenter randomized clinical trial with two arms in patients hospitalized for an AMI nested in the Frenchie registry. Periodontal therapy is performed by periodontists in the intervention group versus treatment by dental surgeons as part of their usual practice in the control group. For the intervention group, periodontal management will …

fdg-pet
18f-fdg
myocardial infarction
  • 1 views
  • 24 Jan, 2021
Imaging of Unstable Carotid Plaque in Patient Referred to Endarterectomy

This study will assess unstable plaque imaging features by using high resolution MR imaging and Sodium Fluoride F-18 PET. This is a comparative study between symptomatic and asymptomatic patient referred to carotid endateriectomy, with reference to pathologic analysis of plaque components

endarterectomy
stroke
fluoride
stenosis
  • 2 views
  • 23 Jan, 2021
  • 1 location
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System

A prospective, multicenter single-arm, open label study to evaluate the safety and effectiveness of the Neuroguard IEP System for the treatment of carotid artery stenosis in subjects at elevated risk for adverse events following carotid endarterectomy (CEA). The Neuroguard IEP System is a 3-in-1 carotid stent delivery system consisting of …

laryngeal nerve paralysis
transient ischemic attack
amaurosis fugax
neurologic symptoms
bypass graft
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1)

This is a phase IV, randomised, placebo-controlled, double-blind, parallel group study to determine the effect of Evolocumab treatment on carotid plaque morphology and composition in asymptomatic patients with >50% carotid artery stenosis.

  • 0 views
  • 27 Jan, 2021
  • 1 location