Found 11 clinical trials
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Multi-country trial
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Phase 3 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL
plus rituximab followed by standard PBSCT (dexamethasone, carmustine, cytarabine, etoposide, and melphalan [Dexa-BEAM]/TBI/high dose cyclophosphamide) in patients with untreated mantle cell
- 134 views
- 07 Nov, 2020
- 2 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Duvelisib Maintenance After Autologous Stem Cell Transplant in T-Cell and Indolent B-Cell Lymphomas
The investigators hypothesize that duvelisib maintenance after autologous stem cell transplant with carmustine, etoposide, cytarabine, and melphalan (BEAM) conditioning in patients with T-cell
- 0 views
- 24 Jan, 2021
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Phase 2 trial
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An interventional trial
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For all genders
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Rheumatology
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Currently Recruiting
Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases
This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a peripheral blood stem cell transplant
- 154 views
- 26 Jan, 2021
- 3 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
A Trial Comparing Single Agent Melphalan to Carmustine Etoposide Cytarabine and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion
The work proposed herein aims to provide the first prospective, randomized comparative efficacy data between Melphalan and BEAM treatment regimen in the Multiple Myeloma (MM) patient population. The risk of such a study is deemed reasonable and ethical since: a) previous works have closely examined the safety and toxicity of …
- 0 views
- 13 Mar, 2021
- 1 location
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Phase 1 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma
structures) and focal radiotherapy. A large number of chemotherapeutic agents (e.g. alkylating agents such as TMZ and nitrosoureas such as carmustine) have also been tested, but they display limited efficacy
- 59 views
- 15 Feb, 2021
- 12 locations
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
This randomized phase III trial studies ibrutinib to see how well it works compared to placebo when given before and after stem cell transplant in treating patients with diffuse large B-cell lymphoma that has returned after a period of improvement (relapsed) or does not respond to treatment (refractory). Before transplant, …
- 149 views
- 15 Apr, 2021
- 143 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
RICE-ibrutinib in Relapsed DLBCL
This is a multicentre, open-label, phase II study of ibrutinib 560 mg in combination with R-ICE for treatment of transplant-eligible relapsed/refractory diffuse large B-cell lymphoma.
- 174 views
- 21 Jan, 2021
- 4 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma
RATIONALE: Giving chemotherapy before a peripheral blood stem cell transplant stops the growth of cancer cells by stopping them from dividing or by killing them. After treatment, stem cells are collected from the patient's blood and stored. More chemotherapy is given to prepare the bone marrow for the stem cell …
- 36 views
- 07 Nov, 2020
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Infections and Infectious Diseases
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Currently Recruiting
Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant
This phase I/II trial studies the side effects and best dose of gene therapy in treating patients with human immunodeficiency virus (HIV)-related lymphoma that did not respond to therapy or came back after an original response receiving stem cell transplant. In gene therapy, small stretches of deoxyribonucleic acid (DNA) called …
- 34 views
- 08 Apr, 2021
- 4 locations
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
NovoTTF-200A Together With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GBM
Study Objectives: To compare the efficacy and safety outcome of newly diagnosed GBM patients treated with NovoTTF-200A concomitant to RT and TMZ to those treated with RT and TMZ alone Study Design: Prospective, randomized, open label, standard of care control Study Hypothesis: The hypothesis of this study is that addition …
- 0 views
- 22 Jan, 2021
- 1
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