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Found 11 clinical trials
Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL

plus rituximab followed by standard PBSCT (dexamethasone, carmustine, cytarabine, etoposide, and melphalan [Dexa-BEAM]/TBI/high dose cyclophosphamide) in patients with untreated mantle cell

dexamethasone
rituximab
measurable disease
high dose chemotherapy
vincristine
  • 134 views
  • 07 Nov, 2020
  • 2 locations
Duvelisib Maintenance After Autologous Stem Cell Transplant in T-Cell and Indolent B-Cell Lymphomas

The investigators hypothesize that duvelisib maintenance after autologous stem cell transplant with carmustine, etoposide, cytarabine, and melphalan (BEAM) conditioning in patients with T-cell

stem cell transplantation
large cell lymphoma
autograft
cytarabine
gilbert's syndrome
  • 0 views
  • 24 Jan, 2021
Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases

This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a peripheral blood stem cell transplant

polyradiculoneuropathy
variable number tandem repeat
polyneuropathy
white blood cell count
apheresis
  • 154 views
  • 26 Jan, 2021
  • 3 locations
A Trial Comparing Single Agent Melphalan to Carmustine Etoposide Cytarabine and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion

The work proposed herein aims to provide the first prospective, randomized comparative efficacy data between Melphalan and BEAM treatment regimen in the Multiple Myeloma (MM) patient population. The risk of such a study is deemed reasonable and ethical since: a) previous works have closely examined the safety and toxicity of …

ejection fraction
melphalan
monoclonal antibodies
serum calcium
monoclonal protein
  • 0 views
  • 13 Mar, 2021
  • 1 location
Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma

structures) and focal radiotherapy. A large number of chemotherapeutic agents (e.g. alkylating agents such as TMZ and nitrosoureas such as carmustine) have also been tested, but they display limited efficacy

nitrosoureas
cancer
chemoradiotherapy
therapeutic agent
carmustine
  • 59 views
  • 15 Feb, 2021
  • 12 locations
Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

This randomized phase III trial studies ibrutinib to see how well it works compared to placebo when given before and after stem cell transplant in treating patients with diffuse large B-cell lymphoma that has returned after a period of improvement (relapsed) or does not respond to treatment (refractory). Before transplant, …

  • 149 views
  • 15 Apr, 2021
  • 143 locations
RICE-ibrutinib in Relapsed DLBCL

This is a multicentre, open-label, phase II study of ibrutinib 560 mg in combination with R-ICE for treatment of transplant-eligible relapsed/refractory diffuse large B-cell lymphoma.

ibrutinib
gilbert's syndrome
glomerular filtration rate
refractory diffuse large b-cell lymphoma
lymphoma
  • 174 views
  • 21 Jan, 2021
  • 4 locations
High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma

RATIONALE: Giving chemotherapy before a peripheral blood stem cell transplant stops the growth of cancer cells by stopping them from dividing or by killing them. After treatment, stem cells are collected from the patient's blood and stored. More chemotherapy is given to prepare the bone marrow for the stem cell …

high dose chemotherapy
cancer
prednisolone
etoposide
carmustine
  • 36 views
  • 07 Nov, 2020
  • 1 location
Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

This phase I/II trial studies the side effects and best dose of gene therapy in treating patients with human immunodeficiency virus (HIV)-related lymphoma that did not respond to therapy or came back after an original response receiving stem cell transplant. In gene therapy, small stretches of deoxyribonucleic acid (DNA) called …

indinavir
ejection fraction
enzyme-linked immunosorbent assay
direct bilirubin
hiv-1 infection
  • 34 views
  • 08 Apr, 2021
  • 4 locations
NovoTTF-200A Together With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GBM

Study Objectives: To compare the efficacy and safety outcome of newly diagnosed GBM patients treated with NovoTTF-200A concomitant to RT and TMZ to those treated with RT and TMZ alone Study Design: Prospective, randomized, open label, standard of care control Study Hypothesis: The hypothesis of this study is that addition …

  • 0 views
  • 22 Jan, 2021