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Found 115 clinical trials
Natural History of COVID-19-Related Atrial Fibrillation

The unCOVer-AF prospective, multicenter registry aims at determining the natural history of atrial fibrillation (AF) via continuous cardiac rhythm monitoring in patients with a first arrhythmic episode during COVID-19 hospitalization.

  • 0 views
  • 29 Nov, 2021
  • 12 locations
NORepinephrine-Maintaining-individuaALIZEd Blood Pressure

This study compares the effect of individualized vs standard blood pressure management on postoperative myocardial injury in high-risk patients undergoing non-cardiac surgery by measuring the hs-cTnT levels. Continuous norepinephrine infusion is used to target a mean pressure of greater than 65mmHg and a systolic pressure less than 160mmHg in the …

  • 0 views
  • 08 Jul, 2022
  • 1 location
Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy

In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours after laparoscopic nephrectomy surgery.

acute pain
anesthesia
bupivacaine
opioid
morphine
  • 0 views
  • 23 Mar, 2022
  • 1 location
Distal Renal Denervation to Prevent Renal Function Decline in Patients With T2DM and Hypertension (REFRAIN)

The aim of this study is to test the hypothesis that distal renal denervation (RDN) may delay or prevent the progressive decline of renal function in patients with type 2 diabetes mellitus and hypertension

type 2 diabetes mellitus
hypertension
glucose tolerance test
kidney function tests
diabetes
  • 1 views
  • 04 Oct, 2022
  • 1 location
Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes

Pancreaticoduodenectomy (PD), more commonly known as Whipple's surgery is the mainstay treatment for pancreatic head and periampullary cancer. Factors contributing to PD outcomes are broadly categorized to disease-related, patient-related and operative factors. Whereas an inexhaustible list of study exists on looking at reducing PD complication rates with respect to the …

periampullary adenocarcinoma
pancreaticoduodenectomy
human albumin
Accepts healthy volunteers
cancer
  • 127 views
  • 05 Jul, 2022
  • 1 location
Functional Capacity in Patients Post Mild COVID-19

Patients recovered from mild coronavirus 2019 (COVID-19) disease without pulmonary involvement may experience long-term physical impairment and dyspnea. The investigators aim to characterize physiologic limitations in patients who recovered from mild COVID-19. Methods: Pulmonary function tests (PFTs), 6-minute walk test (6MWT), echocardiography and cardiopulmonary exercise test (CPET) will be completed …

  • 0 views
  • 19 Apr, 2022
  • 1 location
Clinical Significance of Subclinical Myocardial Involvement in Recovered COVID-19 Patients Using Cardiovascular Magnetic Resonance (R-COVID-CMR)

Introduction Coronavirus disease 2019 (COVID-19) remains a major health issue resulting in >800,000 deaths as of 30th August 2020. A concerning discovery of COVID-19 is the involvement of the myocardium. Several case studies including one from our group (recent study publication in JACC Cardiovascular Imaging led by the principal investigator …

MRI
covid-19
Accepts healthy volunteers
nt-probnp
heart failure
  • 0 views
  • 25 Mar, 2022
  • 1 location
Bariatric Surgery for the Reduction of cArdioVascular Events Feasibility Trial

Pilot multicentre, open-label, parallel-arm randomized controlled trial (RCT) of 60 patients to demonstrate the feasibility of enrolling patients with high-risk cardiovascular disease (CVD) into an RCT of bariatric surgery versus medical weight management (MWM).

body mass index
transient ischemic attack
percutaneous coronary intervention
stroke
diabetes
  • 0 views
  • 04 Feb, 2021
  • 1 location
Comparison of Gastric By-Pass and Optimized Medical Treatment in Obese Diabetic Patients

The objectives are to compare the results of the Gastric By-Pass (GBP) to that of optimized medical therapy in patients with obesity and poorly controlled type 2 diabetes in terms of mortality, weight loss, glycemic control, quality of life, cost, cost-effectiveness and cost utility of these two strategies.

body mass index
diabetes
type 2 diabetes mellitus
glucagon
hemoglobin a1c
  • 72 views
  • 25 Jan, 2021
  • 13 locations
A Phase 2 Study of CC220 (Iberdomide) Combined With Low-dose Cyclophosphamide and Dexamethasone in Relapsed/Refractory Multiple Myeloma (IberCd): ICON Study (ICON)

Evaluation of the effect iberdomide combined with low-dose cyclophosphamide and dexamethasone in patients with relapsed/refractory multiple myeloma.

progressive disease
measurable disease
bone marrow procedure
refractory multiple myeloma
dexamethasone
  • 0 views
  • 27 Oct, 2022
  • 9 locations