Found 281 clinical trials
Pathophysiologic Mechanism for MYOcarditis in COVID19 VAccinations ("MYOVAx" Study) (MYOVAx)
The coronavirus disease 2019 (COVID-19) is an ongoing pandemic which has infected more than 160 million people and caused 3.4 million deaths worldwide till May 2021. With the recent rollout of COVID-19 vaccines globally and in Singapore, reports of rare but serious cardiovascular-related side effects started to appear. Although a …
- 0 views
- 28 Apr, 2022
- 1 location
Randomised Controlled Study of Physical Exercise Intervention in Breast Cancer Patients at Risk of Anthracycline-induced Cardiomyopathy: The EMBRACE Study (EMBRACE)
Cardiomyopathy is a condition that affects the heart muscle, whereby it becomes enlarged, thick or rigid. When the heart muscle becomes involved, it affects the pumping action of the heart. This
- 7 views
- 07 Oct, 2022
- 1 location
Cardiac MRI for the Detection of Myocardial Injury Following Acute Kidney Injury
The aim of this clinical prospective study is to assess structural and functional myocardial changes in patients after acute kidney injury (Cardiorenal syndrome type 3) and intensive care stay by multiparametric cardiac MRI.
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- 12 Sep, 2021
- 2 locations
The Natural History of Danon Disease
Danon disease (DD) is a rare, X-linked disorder associated with severe cardiomyopathy, and in many cases, skeletal myopathy, and cognitive impairment caused by mutations in the LAMP2 gene. There
- 9 views
- 28 May, 2022
- 1 location
Novel ICD Arrhythmia Detection Algorithm
Implantable cardioverter defibrillators (ICD) are used to treat life-threatening heart rhythm disturbances (arrhythmias). They have been proven to reduce the risk of sudden cardiac death however, there are limitations with current ICDs. Firstly, they may deliver inappropriate therapies (therapies delivered in the absence of life-threatening arrhythmias). Secondly, slower life-threatening arrhythmias …
- 0 views
- 06 Aug, 2021
- 1 location
Bern Cardiac Amyloidosis REgistry (B-CARE) (B-CARE)
Cardiac transthyretin amyloidosis (ATTR), caused by ventricular depositions of misfolded transthyretin, results in an infiltrative cardiomyopathy, progressing from pronounced myocardial wall
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- 24 May, 2022
- 1 location
CMR Imaging of Autoimmune Diseases
myocarditis as part of an autoimmune systemic disease will be recruited to ensure that the novel techniques are tested in a broad spectrum of patients with inflammatory heart muscle disease.
- 0 views
- 21 Apr, 2022
- 1 location
Cardio-pulmonary Rehabilitation and Sleep Quality
In this prospective cohort study the investigators aim to evaluate the effect of pulmonary rehabilitation on sleep quality. Disturbed sleep is associated with, frequent exacerbations, increase in the severity of disease and increased mortality in chronic obstructive pulmonary disease (COPD). Sleep quality is a good predictor of quality of life …
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- 19 Apr, 2022
- 1 location
SMART Identification of Ventricular Tachycardia Isthmus (SMARTIS)
Context : Ventricular tachycardia (VT) are serious heart rhythm disorders which can lead to sudden death. A curative treatment for these abnormalities in the cardiac electrical conduction system is possible through an interventional electrophysiology procedure. A catheter is inserted, generally via a femoral access, and is introduced in the heart …
- 0 views
- 05 Sep, 2023
- 1 location
Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)
ICI's have become the first-line treatment for patients with various malignancies. Although case studies represent fulminant myocarditis, there is uncertainty in prevalence of subclinical myocardial injury induced by ICI's. In this prospective study, ICI treatment naïve patients with no significant prior cardiovascular history were enrolled. Primary outcome was the prevalence …
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- 12 May, 2022
- 1 location