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Found 353 clinical trials
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AnaLysIs of Both Sex and Device Specific FactoRs on Outcomes in PAtients with Non-Ischemic Cardiomyopathy - Bio Libra

Secondary Objectives All-cause mortality, VT or VF alone, risk of cardiac death, and sudden cardiac death for the total cohort, as well as by sex and by the implanted device type. Compare the predicted incidence of sudden death using the Seattle Proportional Risk score to the observed incidence in this …

ejection fraction
sudden cardiac death
shock
  • 48 views
  • 24 Nov, 2020
  • 1 location
featured
Clinical, Electrocardiographic, and Cardiac Magnetic Resonance Imaging Risk Factors Associated with Ventricular Tachyarrhythmias in Nonischemic Cardiomyopathy (MARVEN Study)

Implantable cardioverter defibrillator (ICD) for primary prevention of mortality is an approved therapy in ischemic and nonischemic cardiomyopathy patients with left ventricular ejection fraction

heart study
  • 350 views
  • 24 Nov, 2020
  • 1 location
featured
Patients with Heart Failure and currently on a loop diuretic

The purpose of this study is to evaluate the action of the study drug on your kidneys and your ability to eliminate salt and water alongside a diuretic (furosemide). The information gathered during this clinical trial may support further drug development, including larger trials in patients with heart failure.  The study …

furosemide
fatigue
heart failure
  • 88 views
  • 23 Nov, 2020
  • 1 location
Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to determine if LCZ696 is safe, tolerable and can improve exercise capacity (via improved peak VO2) in non-obstructive HCM patient population over the course of 50 weeks of treatment.

cpet
nt-probnp
cardiopulmonary exercise testing
hypertrophy
hypertrophic obstructive cardiomyopathy
  • 2 views
  • 16 Jul, 2021
  • 17 locations
First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy

extension phase in subjects with Amyloid Transthyretin Cardiomyopathy (ATTR-CM).

  • 0 views
  • 20 Aug, 2021
  • 7 locations
Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy

Acute stress-induced (takotsubo) cardiomyopathy or broken heart syndrome presents like a heart attack, classically is triggered by intense emotional or physical stress and can have serious

  • 0 views
  • 25 Jan, 2021
  • 1 location
Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants

The purpose of this Phase 2a study is to establish safety and preliminary efficacy of treatment with danicamtiv in patients with primary dilated cardiomyopathy (DCM) due to MYH7 or TTN variants

  • 0 views
  • 10 Sep, 2021
  • 19 locations
C-MRI Guidance of Implantable CRT-implantation in Non-ischemic Dilated Cardiomyopathy

Patients with diagnostic CMR images for assessment of LGE/fibrosis and evidence/presence of non-ischaemic myocardial fibrosis/scar will be randomized to the following treatment groups in a 1:1 ratio: ICD group or Optimal HF care group.

  • 0 views
  • 29 Jan, 2021
  • 1 location
Biventricular Pacing in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy is an inherited condition characterized by thickening (hypertrophy) of the heart muscle. Many patients who have this condition have a reduced ability to

hypertrophy
heart failure
  • 88 views
  • 07 Nov, 2020
  • 1 location
IVIg Therapy for Patients With Idiopathic Cardiomyopathy and Endomyocardial Biopsy Proven High PVB19 Viral Load

interventional study of virus presence and cardiac functional capacity before and after IVIg therapy. Study population: Patients with idiopathic cardiomyopathy and symptomatic heart failure for

ejection fraction
cardiomyopathy
  • 23 views
  • 07 Nov, 2020
  • 1 location