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Found 37 clinical trials
TrAstuzumab Cardiomyopathy Therapeutic Intervention With Carvedilol (TACTIC)

when significant heart function decline or subtle early signs of heart injury (either by elevation of a cardiac blood biomarker, i.e. cardiac troponin, or by an abnormal heart ultrasound marker, i.e

erbb2
mammogram
lapatinib
pertuzumab
her2/neu-positive breast cancer
  • 1 views
  • 21 Mar, 2022
  • 3 locations
NORepinephrine-Maintaining-individuaALIZEd Blood Pressure

This study compares the effect of individualized vs standard blood pressure management on postoperative myocardial injury in high-risk patients undergoing non-cardiac surgery by measuring the hs-cTnT levels. Continuous norepinephrine infusion is used to target a mean pressure of greater than 65mmHg and a systolic pressure less than 160mmHg in the …

  • 0 views
  • 08 Jul, 2022
  • 1 location
Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics

congenital hearts are very sensitive and irritable to deal with, especially during repair defects, the child's heart is exposed to impaired myocardial function during the entire procedure. Moreover, reperfusion of the heart during open-heart surgery when the myocardium is exposed to a global ischaemic cardioplegic arrest can induce myocardial injury. …

midazolam
ketamine
sevoflurane
cardiac operation
sufentanil
  • 0 views
  • 27 Jul, 2022
  • 1 location
Point-of-care Ultrasound in Suspected Pulmonary Embolism

Pulmonary embolism (PE) is a common cardiovascular condition with an estimated incidence of 0.60 to 1.12 per 1000 inhabitants in the United States of America, and the diagnosis is challenging as patients with PE present with a wide array of symptoms. Computed tomography pulmonary angriography (CTPA) and lung ventilation-perfusion scintigraphy …

assisted ventilation
wells
ctpa
infarct
d-dimer
  • 0 views
  • 15 Jun, 2022
  • 5 locations
Myocardial Contrast Echocardiography in Septic Patients

Myocardial microcirculatory alterations may be involved in the pathogenesis of acute cardiac dysfunction or septic cardiomyopathy in septic patients. The investigators study the cardiac function (systolic and diastolic) with two-dimensional echocardiography (TTE), and the myocardial microcirculation with contrast echocardiography (MCE) and sulphur hexafluoride microbubbles Sonovue injection in ICU septic patients.

resuscitation
vasoconstrictors
dysregulated host response
organ failure
lactate level
  • 0 views
  • 25 Jan, 2021
  • 1 location
Atorvastatin on Inflammation and Cardiac Function in Chronic Chagas Disease

Chagas Disease, caused by the parasite Trypanosoma cruzi afflicts 7 million people in Latin America, and due to migration, abroad. The diagnosis lies in clinical suspicion and serologic detection of antibodies. Cardiac evaluation is essential because complications, including heart failure and arrhythmias, are the main causes of disability and death. …

  • 0 views
  • 24 Nov, 2021
  • 4 locations
Antithrombotic Therapy in Acute Coronary Syndromes and Coronary Artery Ectasia (OVER-TIME)

The optimal anti-thrombotic therapy to prevent recurrent ischemic events in patients with acute coronary syndrome and coronary artery ectasia (CAE) remains unclear. OVER-TIME is an investigator initiated, exploratory, open label, single center, randomized clinical trial comparing dual antiplatelet therapy (acetyl-salicylic acid plus a P2Y12 inhibitor) with the combination of an …

acute coronary syndrome
troponin
clopidogrel
infarct
myocardial infarction
  • 0 views
  • 26 Mar, 2022
  • 1 location
BTE and Pulsed Waveforms for Cardioversion of Atrial Fibrillation - Escalation Strategy and Manual Pressure

Background: A Danish study raised the question of the usefulness of escalating energy protocols compared to fixed high-energy protocols. Maximal energies are usually the final choice of the physicians. Some authors showed that decreasing impedance by manual pressure application (MPA) had a positive impact on cardioversion outcome. This is likely …

cardioversion
fibrillation
shock
  • 0 views
  • 12 Aug, 2022
  • 1 location
Incidence and Outcome of Perioperative Myocardial Injury After Non-cardiac Surgery

This observational study includes patients undergoing major non-cardiac surgery, and screens them for the occurrence of perioperative myocardial injuries (PMI). Incidence, patient characteristics, pathophysiology, potential prevention and therapy strategies and 1-year outcomes of PMI will be described.

  • 26 views
  • 25 Jan, 2021
  • 1 location
Diagnostic and Prognostic Value of Cardiac Biomarkers for Early Coronary Bypass Occlusion in Patients Undergoing Coronary Revascularization

This study is to evaluate the correlation between hs-cTn level as cardiac biomarker for ischemia and early graft occlusion as assessed by CCT in patients undergoing coronary bypass surgery.

  • 0 views
  • 16 Jul, 2021
  • 1 location