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Found 146 clinical trials
Worm Study: Modifier Genes in Sudden Cardiac Death

Quest for modifier genes associated with ventricular arrhythmias in presence of a cardiac sodium channel gene (SCN5A-delPhe1617) mutation.

  • 13 views
  • 21 Jan, 2021
  • 1 location
Psychological Sequelae After Sudden Cardiac Death in the Patient and His Relatives

This study will evaluate and describe the occurrence of Acute traumatic stress and persistence of Post Traumatic Stress Disorder (PTSD) after resuscitated sudden cardiac death (SCD) in patient

anxiety
  • 0 views
  • 20 Jun, 2021
  • 1 location
Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry Disease (RaILRoAD)

Fabry disease (FD) is a genetic disorder that leads to progressive accumulation of fat or 'sphingolipid' within the tissues, including the heart muscle and conductive tissue. Improvements in the detection of FD, together with more organised clinical services for rare diseases, has led to a rapid growth in the disease …

blackouts
cardiomyopathy
replacement therapy
genetic disorder
  • 7 views
  • 16 Jun, 2022
  • 3 locations
Implantable Cardioverter Defibrillator Versus Optimal Medical Therapy In Patients With Variant Angina Manifesting as Aborted Sudden Cardiac Death (VARIANT ICD)

aborted sudden cardiac death reduces the incidence of the death from any cause compared with optimal medical therapy alone.

  • 31 views
  • 24 Feb, 2022
  • 13 locations
Smoking and Ventricular Repolarization

Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization.

Accepts healthy volunteers
  • 7 views
  • 03 Feb, 2022
  • 1 location
The Jewel IDE Study

The Jewel IDE Study: A Clinical Evaluation of the Jewel P-WCD in Subjects at High Risk for Sudden Cardiac Arrest. ("JEWEL")

  • 0 views
  • 15 Jun, 2022
  • 1 location
Impact of an Intensive Care Diary on Post-traumatic Stress Disorder After a Resuscitated Sudden Death

Sudden death is a public health problem with more than 300,000 cases per year in USA and 40,000 cases per year in France. Moreover, despite all recent therapeutic improvements (therapeutic hypothermia, new techniques of resuscitation), the prognosis remains drastically poor and less than 50% of the patients admitted alive at …

amnesia
resuscitation
coma
  • 4 views
  • 24 Jan, 2021
  • 2 locations
Hematopoietic Stem Cell Transplant for Sickle Cell Disease

This is a phase I/II study of patients with sickle cell disease. It aims to find out if people with sickle cell disease can be cured by changing their immune system before they have blood stem cell transplants. Doctors will give patients a new drug (fludarabine) to see if this …

conjugated bilirubin
thalassemia
sirolimus
sickle hemoglobin
hemoglobin c disease
  • 84 views
  • 14 Jun, 2022
  • 1 location
Optimization of VNS in Epileptic Patients to Induce Cardioprotection

This study is a non-randomized, prospective study in patients with a diagnosis of epilepsy and previously implanted FDA approved Vagus Nerve Stimulation (VNS) devices. The goal of this clinical investigation is to evaluate the effects of adjusting vagus nerve stimulation parameters to engage cardioprotective effects.

seizure
vagus nerve stimulation
  • 0 views
  • 07 Oct, 2021
  • 1 location
Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot

Individuals with repaired Tetralogy of Fallot (rTOF) remain at risk for sudden cardiac death from ventricular tachycardia (VT). Transcatheter pulmonary valve replacement (TPVR) indications

  • 0 views
  • 18 Mar, 2022
  • 1 location