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Found 59 clinical trials
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure - An Investigator-initiated, Event-driven, Prospective, Parallel-group, Randomised, Open, Blinded Outcome Assessment (PROBE), Multi-centre Trial Without Investigational Medical Products (Proof of Strategy Trial) (RESET-CRT)

Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

cardiac resynchronization therapy
cardiomyopathy
ejection fraction
medical therapy
  • 2 views
  • 25 Oct, 2022
  • 173 locations
Left Bundle Branch Area Pacing Using Conventional Stylet Driven Pacemaker Leads for Cardiac Resynchronization Therapy: A Randomized Study (LeCaRT)

The aim of this study proposal is to compare the effectiveness of two distinct pacing modalities for cardiac resynchronization therapy. Our primary hypothesis is that left bundle branch area

  • 0 views
  • 21 Oct, 2022
  • 2 locations
Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients (METEOR-CRT)

Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular

cardiac resynchronization therapy
ejection fraction
medical therapy
  • 0 views
  • 14 Jun, 2022
  • 2 locations
Effects of CRT Optimization as Assessed by Cardiac MR

Cardiac resynchronization therapy (CRT), or atrial-synchronized biventricular (BiV) pacing, is an FDA-approved device therapy option for heart failure (HF) patients with reduced left ventricular

  • 0 views
  • 04 Oct, 2021
  • 2 locations
A Phase 1b Double-blind, Randomized, Placebo-controlled, Multicenter, Dose Titration Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of 4 Weeks Treatment With BAY 2413555 in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (REMOTE-HF)

participants with chronic heart failure and implanted cardiac defibrillator, or cardiac resynchronization devices (ICD/CRT). A placebo is a treatment that looks like a medicine, but does not have any medicine

  • 0 views
  • 25 Oct, 2022
Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair

The investigators' hypothesis is that CMR tissue characterization and myocardial function analysis acquired by CMR feature tracking technique predict reverse remodeling in patients with severe secondary mitral regurgitation (MR) undergoing transcatheter mitral edge-to-edge repair.

  • 0 views
  • 05 Sep, 2021
  • 1 location
Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy (ASTRAL-4LV)

The primary objective of this study is to assess the chronic safety and performance of the Axone left ventricular (LV) micro-lead.

cardiac resynchronization therapy
  • 0 views
  • 28 Oct, 2022
  • 19 locations
SyncAV Post-Market Trial (SyncAV)

The SyncAV Post-Market Trial is a prospective, randomized, multi-center trial performed to determine if cardiac resynchronization therapy (CRT) devices programmed with SyncAV ON improve long

cardiac resynchronization therapy
implantable cardioverter-defibrillators
heart failure
angiotensin
beta blockers
  • 0 views
  • 07 Oct, 2022
  • 101 locations
Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 75 Years (DILEMMA)

months after randomization, in patients ≥ 75 years with an ICD indication for primary prevention of SCD whether there is an indication for cardiac resynchronization therapy or not.

heart failure
sudden cardiac death
ejection fraction
medical therapy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Mechanical Dyssynchrony as Selection Criterion for CRT

Previous experience with cardiac resynchronization therapy (CRT) candidates suggests that selection of these patients can be improved. Current clinical guideline approaches are mainly too

cardiac resynchronization therapy
  • 0 views
  • 16 Oct, 2021
  • 8 locations