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Found 33 clinical trials
Effectiveness of a Proactive Cardiovascular Primary Prevention Strategy, With or Without the Use of Coronary Calcium Screening, in Preventing Future Major Adverse Cardiac Events (CorCal)

The primary objective of this study is to test the effectiveness of a proactive cardiovascular primary prevention strategy, with or without the use of coronary calcium screening, compared to current standard care, in preventing future major adverse cardiac events (MACE), including all-cause death, non-fatal myocardial infarction (MI), stroke, or any …

Accepts healthy volunteers
  • 0 views
  • 26 Feb, 2022
  • 1 location
Limitations of Aerobic Capacity in Chronic Heart Failure

This study will use a novel CPX test that incorporates instantaneous assessment of maximal isokinetic cycling power at VO2peak to elucidate the mechanisms that limit VO2peak in CHF, and compare these responses with age-matched controls.

Accepts healthy volunteers
  • 0 views
  • 03 Mar, 2022
  • 1 location
Drug-coating Balloon Angioplasties for True Coronary Bifurcation Lesions

composite endpoint of major adverse cardiac event (MACE) at 12 months. The individual components of MACE include cardiac death, myocardial infarction (MI), or target lesion revascularization (TLR). True

myocardial infarction
angiography
chest pain
revascularisation
ischemia
  • 0 views
  • 17 Nov, 2021
  • 1 location
Atrial Sensing Capability for Better Detection of Atrial Fibrillation

This prospective multi-center randomized controlled study aims to compare atrial fibrillation detection and inappropriate therapy according to activation of atrial sensing capability in patients with implantable cardioverter defibrillator.

electrocardiogram
implantable cardioverter-defibrillators
fibrillation
  • 0 views
  • 10 Oct, 2021
  • 28 locations
Assessment of Adverse Outcome in Asymptomatic Patients With Prior Coronary Revascularization Who Have a Systematic Stress Testing Strategy Or a Non-testing Strategy During Long-term Follow-up.

myocardial ischemia may help prevent a major acute cardiac event. However, systematic screening strategy is costly and there is currently no evidence that repeated revascularization improve survival

cardiac event
revascularisation
ischemia
coronary revascularization
exercise stress test
  • 0 views
  • 28 Nov, 2021
  • 1 location
Treatment of Cardiovascular Disease With Low Dose Rivaroxaban in Advanced Chronic Kidney Disease

cardiac event (MACE) in people with Chronic Kidney Disease (CKD) stages 4 or 5 or dialysis-dependent End Stage Kidney Disease (ESKD), and elevated cardiovascular (CV) risk, whilst maintaining an

dialysis
  • 2 views
  • 22 Dec, 2021
  • 34 locations
Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

This is a multicenter, randomized, placebo-controlled, 2-part study to evaluate the safety and efficacy of AT-001 in adult patients (N=675) with Diabetic Cardiomyopathy at high risk of progression to overt heart failure.

heart failure
nt-probnp
  • 0 views
  • 11 Mar, 2022
  • 79 locations
Remote Exercise SWEDEHEART Study

The overall aim of the study is to evaluate if remote video exercise-based cardiac rehabilitation (exCR), offered as an alternative to centre-based exCR, can increase the proportion of patients post myocardial infarction (MI) successfully completing an exCR-program.

acute myocardial infarction
myocardial infarction
cardiac rehabilitation
infarct
  • 12 views
  • 01 May, 2022
  • 16 locations
Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BAT (MINOCA-BAT)

Myocardial infarction with non-obstructive coronary arteries" (MINOCA) occurs in 5-10% of all patients with AMI. There are neither any randomized clinical trials in MINOCA patients evaluating effects of secondary preventive treatments proven beneficial in patients with classic AMI, nor any treatment guidelines. The primary objective of this multi-national, multi-center pragmatic …

  • 6 views
  • 04 Feb, 2022
  • 18 locations
Preventing Adverse Cardiac Events in COPD

A double-blind, randomised controlled trial in participants with COPD to assess the efficacy of proactive treatment of cardiac risk in people with COPD. We hypothesise that treating known and undiagnosed CVD in COPD participants will improve both cardiac and respiratory outcomes.

heart failure
hypertension
bronchodilator
coronary disease
copd exacerbation
  • 76 views
  • 25 Jan, 2021
  • 17 locations