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Found 161 clinical trials
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Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

The PROTECT-ICD trial is a physician-led, multi-centre randomised controlled trial targeting prevention of sudden cardiac death in patients who have poor cardiac function following a myocardial

  • 123 views
  • 18 Oct, 2021
  • 37 locations
None
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

  • 32 views
  • 30 Nov, 2021
  • 293 locations
None
China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome

In summary, the CHILLAS study will be the first multicenter study performed in a Chinese population using a patient-level analysis to compare the effects and safety of intensive statin therapy with that of moderate statin therapy. Therefore, it will determine whether "lower is better", that is, whether LDL cholesterol lowering …

atorvastatin
LDL Cholesterol
hmg-coa reductase inhibitor
intravascular ultrasound
low density lipoprotein
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with regards to the primary endpoint failed first shock in a spontaneous arrhythmia episode when implant position is confirmed with PRAETORIAN …

  • 79 views
  • 25 Jan, 2021
  • 41 locations
None
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac Resynchronisation Therapy, the implantation of a pacemaker (index group) is not inferior to defibrillator (control group) with respect to all-cause mortality.

cardiomyopathy
cardiac resynchronization therapy
medical therapy
ejection fraction
  • 2 views
  • 15 Nov, 2021
  • 360 locations
None
Improvement in Baroreflex Sensitivity in OSAS

airway pressure (CPAP) on daytime baroreflex sensitivity (BRS), a predictor of cardiac death, was investigated in OSAS patients.

continuous positive airway pressure
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
Effect of Angiotensin-Neprilysin Inhibition (ARNI) on Prognosis of Chronic Heart Failure

divided into Angiotensin-Neprilysin Inhibition (ARNI) group and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACEI/ARB) group. All-cause death, cardiac death and re

nt-probnp
ace inhibitor
enalapril
entresto
angiotensin
  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Influence of Sacubitril/Valsartan on Autonomic Cardiac Nervous System in Heart Failure Patients: an Exploratory Study

failure with reduced ejection fraction show impaired heart rate variability, knowing that in these patients such impairment is highly associated with an increased risk of sudden cardiac death. In

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Polish-Italian-Hungarian RAndomized ThrombEctomy Trial

: measurement of left ventricular end-diastolic EDV and end-systolic volumes ESV, ejection fraction (EF) and wall motion score index (WMSI) Major cardiac events /cardiac death, reMI, rePCI (TVR, TLR

percutaneous coronary intervention
cardiac death
coronary artery bypass graft
acute myocardial infarction
cardiac event
  • 20 views
  • 07 Nov, 2020
  • 3 locations
None
Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis

, lymph nodes and the heart. In this latter case, cardiac sarcoidosis (CS) can lead to atrioventricular (AV) blocks, ventricular arrhythmias, heart failure (HF) and sudden cardiac death. Similar to other

  • 7 views
  • 16 Nov, 2021
  • 2 locations