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Found 28 clinical trials
A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma

carcinosarcoma. The researchers will also look at the safety of the drug combination and whether it causes few or mild side effects in participants.

  • 0 views
  • 11 Mar, 2022
  • 1 location
Pazopanib vs. Pazopanib Plus Gemcitabine (PazoDoble)

This study is a prospective, randomized, open-label, multicenter phase II trial in order to determine progression-free survival of patients with refractory or relapsed metastatic uterine leiomyosarcomas or other metastatic uterine tumours.

  • 2 views
  • 12 Feb, 2022
  • 3 locations
ATr Inhibitor in Combination With Olaparib in Gynaecological Cancers With ARId1A Loss or no Loss (ATARI)

ATARI trial tests the ATR inhibitor drug AZD6738 and a PARP inhibitor drug olaparib in patients with relapsed gynecological cancers to assess the response in groups of patients selected based on their cancer cell subtype and the presence of an abnormality in ARID1A gene.

  • 6 views
  • 19 Feb, 2022
  • 1 location
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

carcinoma (temporarily closed to accrual 04/29/2020) Clear cell cervical cancer Esthenioneuroblastoma (closed to accrual) Endometrial carcinosarcoma (malignant mixed Mullerian

trophoblastic disease
teratoma
serous adenocarcinoma
pancreatic adenocarcinoma
cns disease
  • 6621 views
  • 25 May, 2022
  • 767 locations
Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus

Aim To investigate the effect of sentinel lymph node (SLN) sampling on the prognosis of patients with middle-high risk endometrial cancer obviously confined to the uterus before surgery.

  • 0 views
  • 09 Apr, 2022
  • 1 location
Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or Carcinosarcoma

This study is to explore the treatment of advanced sarcomatoid carcinoma or Carcinosarcoma with Carrelizumab combined with Apatinib, in order to provide guidance and experience for new combined

metastasis
apatinib
serum bilirubin
neutrophil count
carcinoma
  • 0 views
  • 06 Mar, 2022
  • 1 location
ZW25 in Women With Endometrial Cancers

This study is being done to test the drug ZW25 and look at whether this drug is effective in women with HER2-overexpressed endometrial cancer or carcinosarcoma that has been treated in the past

endocrine therapy
maintenance therapy
antibiotics
formalin-fixed paraffin-embedded
x-rays
  • 0 views
  • 24 Mar, 2022
  • 7 locations
Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.

Advanced technology has enabled radiation oncologists to more accurately and precisely target radiation to areas at risk while maximally sparing healthy tissue. Furthermore, there is growing evidence demonstrating both safety and efficacy for SBRT. We propose that these advantages are translatable to the adjuvant treatment of endometrial cancer. We submit …

uterine disease
immunomodulators
adenocarcinoma
systemic therapy
hysterectomy
  • 0 views
  • 26 Jan, 2021
  • 1 location
(VELA) Study of BLU-222 in Advanced Solid Tumors

This is a Phase 1/2, open-label, first-in-human (FIH) study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and anticancer activity of BLU-222, a selective inhibitor of CDK2.

erbb2
cancer of the ovary
HER2
ovarian cancer
carboplatin
  • 0 views
  • 11 Mar, 2022
  • 1 location
Nivolumab for Recurrent/Metastatic Carcinosarcoma

Carcinosarcoma is a malignant neoplasm that is composed of both epithelial and mesenchymal elements and aggressive tumor that are staged as high-grade cancer in NCCN guideline. They are regarded

  • 0 views
  • 26 Mar, 2022
  • 1 location