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Found 99 clinical trials
Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

The main goal of this phase of the study is to determine if objectively assessed Physical Activity (PA) levels in advanced-cancer patients are associated with health care provider (HCP)-assessed ECOG performance status and overall survival. The purpose is to advance the evidence-base for incorporating objective assessment of Physical Activity (PA) …

primary cancer
cyst
cavity
radiation oncology
cancer
  • 43 views
  • 18 Feb, 2021
  • 1 location
A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck

The purpose of this study is to determine the efficacy of nivolumab + cisplatin-RT relative to standard of care (SOC) cisplatin-RT alone, using the disease-free survival (DFS by investigator imaging assessment) as primary endpoint )

EGFR
squamous cell carcinoma
cavities
caries
carcinoma
  • 5 views
  • 24 Feb, 2021
  • 1 location
Transmission Reduction and Prevention With HPV Vaccination (TRAP-HPV) Study

Human papillomavirus (HPV) is a member of the Papillomaviridae family of DNA viruses that is capable of infecting humans. HPV infection can cause cancers of the cervix, vulva, vagina, and anus in women or cancers of the anus and penis in men. Two prophylactic vaccines have been proven to be …

hpv vaccine
human papillomavirus
cancer
gardasil
vaccination
  • 9 views
  • 26 Jan, 2021
  • 1 location
Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer

This prospective study aims to utilize pre- and mid-treatment PET-CT to guide de-escalation of radiation therapy in HPV-related squamous cell carcinoma of the oropharynx.

oropharyngeal carcinoma
squamous cell carcinoma
oropharyngeal squamous cell carcinoma
carcinoma
carboplatin
  • 5 views
  • 01 Feb, 2021
  • 2 locations
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as

squamous cell carcinoma
human papillomavirus
neck dissection
carcinoma
primary tumor
  • 0 views
  • 23 Jan, 2021
Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer

neck in human papilloma associated oropharynx cancer vs. the current standard 7-week course chemoradiation.

oropharyngeal carcinoma
squamous cell carcinoma
oropharyngeal squamous cell carcinoma
carcinoma
primary tumor
  • 55 views
  • 04 Mar, 2021
  • 1 location
Assessment of Swallowing Function and Quality of Life in Oropharyngeal Cancer Patients Treated by Chemo-radiotherapy

Open-label, interventional, multicentric, randomized, phase III study. Cancer studied is the oropharyngeal cancer. Study is composed by 2 arms of subjects: prophylactic or reactive

squamous cell carcinoma
tube placement
carcinoma
renal function test
neutrophil count
  • 0 views
  • 24 Jan, 2021
  • 2 locations
De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma

The purpose of this study is to find out whether radiotherapy to some of the lymph node areas can be safely omitted to decrease side effects without increasing the risk of the tumour coming back.

ct scan
squamous cell carcinoma
oropharyngeal squamous cell carcinoma
cancer
carcinoma
  • 48 views
  • 23 May, 2021
  • 14 locations
Feasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer

The aim of this research is to study the feasibility of neoadjuvant treatment before chemoradiation in "high risk" HPV-driven Oropharynx cancer

squamous cell carcinoma
oropharyngeal squamous cell carcinoma
measurable disease
carcinoma
chemoradiotherapy
  • 1 views
  • 24 May, 2021
  • 12 locations
Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers

This study is to determine whether a mathematical model can be used to choose a radiation delivery method to improve the rate of a rapid response.

oropharyngeal carcinoma
squamous cell carcinoma
metastasis
measurable disease
cancer
  • 4 views
  • 21 May, 2021
  • 1 location