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Found 40 clinical trials
Abemaciclib in Treating Patients With Advanced, Refractory, and Unresectable Digestive System Neuroendocrine Tumors

This phase II trial studies how well abemaciclib works in treating patients with digestive system neuroendocrine tumors that have spread to other places in the body, do not respond to treatment, and cannot be removed by surgery. Abemaciclib may stop the growth of tumor cells by blocking some of the …

gilbert's syndrome
platelet count
metastatic cancer
carcinoid tumor
neuroendocrine tumor
  • 4 views
  • 04 Oct, 2022
  • 1 location
EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

This study is to evaluate the safety and antitumor activity of EMB-01 in advanced/metastatic gastrointestinal cancers, including gastric cancer, hepatocellular cancer, cholangiocarcinoma and colorectal cancer.

EGFR
cancer
tyrosine
measurable disease
bone metastases
  • 0 views
  • 06 May, 2022
  • 4 locations
Combination Immunotherapy in Rare Cancers Under InvesTigation (MOST-CIRCUIT)

into four groups: Neuroendocrine cancers: Atypical bronchial carcinoid, neuroendocrine carcinoma and Grade 3 NETs independent of primary site (SCLC excluded) Biliary tract

  • 4 views
  • 04 Oct, 2022
  • 10 locations
AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

This pilot trial studies how well telotristat etiprate works in treating participants with well differentiated neuroendocrine neoplasm that has spread to other places in the body and monitored by carbon C 11 alpha-methyltryptophan (AMT)-emission tomography (PET). Telotristat etiprate may stop the growth of tumor cells by blocking some of the …

  • 1 views
  • 21 Apr, 2022
  • 1 location
Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary Pheochromocytoma Paraganglioma Unknown Primary Thymus NETs (PUTNET) or Any Other Non-.GEP-NET.

Determine the safety and effectiveness of Lu-177 DOTATOC in adult subjects with somatostatin receptor-expressing Pulmonary, Pheochromocytoma, Paraganglioma, Unknown primary, and Thymus neuroendocrine tumors or any other non-.GEP-NET. The treatment regimen will consist of 4 doses of 200 (10%) mCi 177Lu-DOTATOC administered at 8+/- 1-week intervals.

18f-fdg
paraganglioma
MRI
octreotide
fdg pet/ct
  • 0 views
  • 18 Jul, 2021
  • 1 location
A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus Sunitinib or PRRT (CABOTEM)

The aim of CABOTEM study is to demonstrate the safety and activity of the Cabozantinib and Temozolomide combination in Lung and GEP-NENs patients, progressing after a first line therapy, including target therapies (everolimus, sunitinib) and / or chemotherapy, in the approved setting.

  • 0 views
  • 20 Oct, 2021
  • 1 location
Dual SSTR2 and Integrin αvβ3 Targeting PET/CT Imaging

This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluate the efficacy of 68Ga-NOTA-3PTATE-RGD in lung cancer patients and neuroendocrine neoplam patients. A single dose of 111-185 Mega-Becquerel (MBq) 68Ga-NOTA-3P-TATE-RGD will be injected intravenously. Visual and semiquantitative method will be used to assess …

x-rays
ct scan
lung carcinoma
Accepts healthy volunteers
lung cancer
  • 0 views
  • 20 Apr, 2022
  • 1 location
Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma: a Prospective Exploratory Trial (TESLA II)

The study will investigate whether liver transplantation provides increased survival, low side effects and good quality of life in patients with bile duct cancer where the tumor cannot be removed by normal surgery. Analyzes of blood and tissue samples from the tumor will be investigated to see if the analyzes …

  • 0 views
  • 14 Oct, 2022
  • 1 location
Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma

Low blood sugars are known to cause brain damage in newborn babies. One of the most common causes of low blood sugars persisting beyond the new born period is a condition called congenital hyperinsulinism (HI). This is a disease whereby the pancreas secretes too much insulin and causes low blood …

  • 4 views
  • 23 Jan, 2021
  • 1 location
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Background Pheochromocytoma and paraganglioma are rare tumors. They usually form inside and near the adrenal gland or in the neck region. Not all these tumors can be removed with surgery, and there are no good treatments if the disease has spread. Researchers think a new drug may be able to …

18f-fdg
adrenaline
paraganglioma
fdg pet/ct
progressive disease
  • 6 views
  • 27 Oct, 2022
  • 1 location