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Found 97 clinical trials
Phase 1/2 Study of SBRT With or Without GC4711 for NSCLC

GTI-4711-101 is a Phase 1-2 study of the safety of GC4711, and its potential to reduce radiation-related pulmonary injury due to SBRT for early stage large or central localized NSCLC. After an open-label, Phase 1, safety cohort of approximately 5 subjects has been completed, a randomized, double-blind, placebo-controlled Phase 2 …

  • 0 views
  • 07 Mar, 2021
  • 3 locations
Effect of the SCOT-HEART 2 Trial on Lifestyle.

This study will recruit 400 participants who are taking part in the Computed Tomography Coronary Angiography for the Prevention of Myocardial Infarction (SCOT-HEART 2) trial. The investigator will assess diet, activity and habits at the start of the study and 6 months later. This will help us understand the effects …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Effects of Filter Ventilation and Ventilation Information on Product Use Behaviors in Cigarette Smokers

This clinical trial collects data to see how filter ventilation and ventilation information affects product use behaviors in cigarette smokers. Providing ventilation information on the cigarette package may affect smokers' rating of product appeal, perceptions of health risk, and changes in cigarette consumption.

  • 0 views
  • 19 Feb, 2021
  • 1 location
Pilot Study to Evaluate the Safety Tolerability and Efficacy of 5-ALA-Phosphate + SFC in Subjects With COVID-19

This is an open-label, interventional exploratory study to evaluate the safety and efficacy of 5-ALA-Phosphate + SFC in subjects with acute moderate or severe respiratory illness secondary to infection with SARS-CoV-2 virus (COVID-19) involving 40 subjects. The primary objective is to evaluate the safety of 4-week oral administration of 5-ALAPhosphate …

  • 0 views
  • 05 Mar, 2021
  • 2 locations
Adverse Airway Effects From Tobacco and E-Cigarettes

The purpose of the study conducted at VA Medical Center in Miami is to determine if smoking electronic cigarettes (known as e-cigarettes) that contain nicotine have less negative effects than regular cigarettes on the person's respiratory health. We will assess this by measuring pulmonary function tests, several body molecules and …

tobacco smoke
  • 108 views
  • 21 Jan, 2021
  • 1 location
SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

SEACOAST 1 is a prospective, randomized, blinded endpoint trial comparing collateral vigor and clinical outcomes, with different forms of GA in patients with acute ischemic stroke due to anterior circulation large vessel occlusion (LVO) undergoing mechanical thrombectomy. The study compares GA with normocarbia (GAN) versus GA with mild hypercarbia (GAH), …

experimental drug
subarachnoid hemorrhage
angiography
anesthesia
ischemic stroke
  • 0 views
  • 23 Jan, 2021
  • 1 location
Ixazomib Citrate Lenalidomide and Dexamethasone in Treating Patients With POEMS Syndrome

This pilot clinical trial studies how well ixazomib citrate, lenalidomide, and dexamethasone work in treating patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, …

platelet count
dexamethasone
neutrophil count
bone marrow procedure
chemotherapy regimen
  • 1 views
  • 25 Jan, 2021
  • 1 location
A Healthy People Initiative: Building the Socio-Economic Capital of Low Income Population At-Risk for HIV and Hepatitis-C

"Health is a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity" (World Health Organization, 1948). Diseases such as HIV/AIDS and Hepatitis-C (HCV) thrive in conditions of poverty and marginalization. Research on the quality of life of people living with HIV/AIDS reveals …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment

Smoking cessation has been shown to improve the effectiveness and reduce the morbidity of tobacco-related cancer treatments. We will identify effective smoking cessation strategies for patients who are receiving treatment for tobacco-related cancer. In this trial, patients' preferences in smoking cessation therapy will be the principal determinant by providers in …

  • 0 views
  • 03 Feb, 2021
  • 1 location
SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects

This is a single arm, multi-centre, phase II open label study of nivolumab with stereotactic body radiotherapy (SBRT) for early stage non-small cell lung cancer. SBRT will be delivered in either 3 or 5 fractions. A flat dose of 240 mg nivolumab infusion will begin after the final fraction of …

  • 0 views
  • 24 Jan, 2021
  • 1 location