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Found 99 clinical trials
Early Rheumatoid Arthritis Lung Disease Study

The primary goal of this study is to investigate lung disease, through pulmonary function and high resolution chest CT, in newly diagnosed RA patients. Extra-articular disease occurs in approximately 50% of RA patients, with the lung being a common site of involvement. Investigators goal is to understand the prevalence of …

arthropathy
  • 5 views
  • 25 Jan, 2021
  • 1 location
Electronic Cigarette Use During Pregnancy

Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2. To compare toxicant exposure and birth outcomes among infants born to pregnant women who use e-cigs compared to women …

  • 36 views
  • 02 May, 2021
  • 6 locations
Healthy Lung Study- Development of 3 Tesla MRI Hardware and Software for Helium-3 Gas Imaging of the Lung: Healthy Volunteer Development Study

Healthy volunteers aged 18-75 will undergo hyperpolarized 3-Helium MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.

  • 235 views
  • 25 Jan, 2021
  • 1 location
Lung Function Exercise Capacity and Serology Responses in Patients With COVID-19

(a) Objectives To assess the full lung function, exercise capacity, quality of life in patients with COVID-19 over 2 years. To assess the longevity of the serology response to SARS-CoV2.

  • 0 views
  • 26 Jan, 2021
COVID-19: Respiratory and Sleep Follow-up

The current project is a prospective, multicentric cohort study aiming at a multidisciplinary assessment (pulmonary, cardiometabolic, sleep and mental health) of the consequences of infection by SARS-CoV-2, 3 months after the diagnosis in order to better characterize these complications. 400 patients with a positive diagnosis of SARS-CoV-2 will be included …

covid-19
SARS
  • 0 views
  • 24 Jan, 2021
  • 4 locations
Lung Function Exercise Capacity and Health-Related Quality of Life After Severe COVID-19

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus (SARS-CoV-2) that can progress to severe disease requiring hospitalization and oxygen support in around14% of the cases and 5% require admission in intensive care unit. The medium and long-term impact in survivors of severe COVID-19 …

respiratory symptom
fever
acute respiratory distress
SARS
FIO2
  • 0 views
  • 08 May, 2021
  • 5 locations
Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of COPD

This is a prospective study to determine the relationships between pauci-inflammatory exacerbations and diastolic dysfunction, and their implications in hospitalized patients with acute exacerbations of COPD. To assess changes within subjects from stable to acute phase, a number of comparisons will be made in subjects enrolled during acute exacerbation with …

COPD
acute exacerbation of copd
acute exacerbation of chronic obstructive pulmonary disease
  • 7 views
  • 24 Jan, 2021
  • 1 location
Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19

A novel corona virus emerged in 2019 causing Corona Virus Disease 2019 (covid-19). In one year more than 80 000 000 cases worldwide were documented. Some patients experience symptoms, specifically shortness of breath, long after the viral infection has passed. These patients are colloquially known as "Covid-19 Long-Haulers" and it …

  • 0 views
  • 19 Mar, 2021
  • 1 location
Characterization of Patients With Tuberous Sclerosis Complex Lymphangioleiomyomatosis and Angiomyolipoma

Tuberous Sclerosis Complex (TSC) is a multisystemic autosomal dominant disease that is characterized by the development of benign neoplasms in brain, kidney, lung, skin and heart. TSC is caused by mutations in TSC1 and/or TSC2 genes, which encode, respectively, hamartin and tuberin, that are involved in the regulation of cell …

astrocytoma
mammalian target of rapamycin
angiofibroma
lymphangioleiomyomatosis
angiomyolipoma
  • 7 views
  • 25 Jan, 2021
  • 1 location