Found 90 clinical trials
A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV
Many people living with HIV (PLWH) smoke. Smoking in these individuals is often undertreated. This study plans to assess the ability of various clinical pathways involving tobacco treatment medications and contingency management (paying smokers for not smoking) to improve smoking cessation in a group of PLWH.
- 0 views
- 01 Sep, 2021
- 3 locations
The Role of High-flow Nasal Cannula Therapy in the Treatment of Acute Carbon Monoxide Poisoning
The aim of the study is to test whether oxygen therapy delivered through high-flow nasal cannula devices in patients admitted to the emergency department for acute carbon monoxide poisoning is
- 0 views
- 22 Jan, 2021
Assessing Electronic Cigarette Nicotine Flux
The purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an
- 0 views
- 17 Feb, 2021
- 1 location
Development of a New Method for Steady-State Measurement of NO Lung Diffusing Capacity in Healthy Subjects
-45 years). The results will be compared to those measured by using carbon monoxide single-breath estimates. We like to show that the new method is sufficient to measure exactly lung
- 4 views
- 07 Nov, 2020
- 1 location
Pulmonary Diffusing Capacity During Postural Postural Changes and Acute Exercise
The combined measurement of the pulmonary diffusing capacity to carbon monoxide (CO) and nitric oxide (NO) (DLCO/NO) has recently been standardised and validated for clinical use. It involves a
- 0 views
- 20 Sep, 2021
- 1 location
Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy
Hyperbaric oxygen therapy (HBOT) utilizes 100% oxygen delivery at a pressure greater than 1 atm for the treatment of various emergent medical conditions including carbon monoxide poisoning. The
- 0 views
- 05 Jun, 2021
- 1 location
The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans
has highlighted that increased capillary blood volume (Vc) and diffusion capacity for carbon monoxide (DLCO) are correlated with higher cardiorespiratory fitness at rest. Additionally, endurance
- 0 views
- 19 Sep, 2021
- 1 location
Varenicline for Long-term Nicotine Replacement Therapy (NRT) Users
Primary aim: Will varenicline be better than placebo to get long-term users of NRT to stop? Secondary aim: To assess in details some side effects of varenicline i.e. nausea and abnormal dreams.
- 48 views
- 08 Nov, 2020
- 1 location
Non-Myeloablative Allogeneic Transplantation From Unrelated Donors in Multiple Myeloma
The protocol aims at reducing transplant toxicity and mortality in patients with multiple myeloma.
- 4 views
- 07 Nov, 2020
- 1 location
Smoking Cessation Program in the Preadmission Clinic
This study is a randomized, double-blind, placebo-controlled clinical trial which evaluates the efficacy of preoperative smoking counseling and varenicline (a medication approved by Health Canada and FDA for quitting smoking) to provide long term smoking cessation (i.e., abstinence for at least one year) in surgical patients. The primary hypothesis is …
- 106 views
- 08 Nov, 2020
- 1 location