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Found 8 clinical trials
Study of the Effects of Itraconazole and Carbamazepine on LY3410738 in Healthy Participants

The main purpose of this study is to learn about how itraconazole and carbamazepine affect the levels of LY3410738 in the blood stream of healthy participants. Participation could last up to 75

Accepts healthy volunteers
  • 0 views
  • 24 Apr, 2022
  • 1 location
A Study of Steady-state Carbamazepine on the Single-dose of Erdafitinib Tablets in Healthy Adult Participants

The main purpose of this study is to evaluate the effect of multiple doses of carbamazepine (a strong inducer of cytochrome P450 [CYP]3A4 and a weak inducer of CYP2C9) on the pharmacokinetics of

Accepts healthy volunteers
  • 230 views
  • 15 Mar, 2022
  • 1 location
Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity

-blinded administration of four known and studied pharmacological agents known to safely induce changes in the motor cortex, as well as a placebo. Investigators will use carbamazepine (sodium channel

  • 0 views
  • 22 Jun, 2021
  • 1 location
The Safety of Paxlovid in Hemodialysis Patients With Covid-19 (SPHPS)

Infection with SARS-CoV-2 continue to threaten global health. Persons with chronic kidney disease, including dialysis treatment are at hight risk for severe Covid-19 and associated adverse outcomes. Paxlovid (Nirmatrelvir/Ritonavir) decreases risk of progression to severe Covid-19. It is not recommended for dialysis patients because due to lack of data. The …

  • 0 views
  • 23 May, 2022
Pirfenidone Compared to Placebo in Post-COVID19 Pulmonary Fibrosis COVID-19

Study population: Patients with fibrotic lung sequelae after recovery from acute phase of severe COVID19 pneumonia Objectives: To evaluate the effect of pirfenidone administered for 24 weeks in patients who have pulmonary fibrotic changes after suffering severe COVID19 pneumonia, analysed by % change in forced vital capacity (FVC) % fibrosis …

  • 11 views
  • 09 Jan, 2022
  • 3 locations
DTG Plus 3TC for Prophylaxis of Mother-to-child Transmission of HIV Infection in Pregnant Women (PREGNANT)

The study aims to evaluate the safety and efficacy of a 2 drugs ART regimen (lamivudine plus dolutegravir) for prevention of mother to child transmission in pregnant women with HIV. 20 pregnant women will be enrolled in this proof of concept protocol. They will be prescribed DTG-3TC (fixed-dose combination), and …

lamivudine
Accepts healthy volunteers
mother-to-child transmission
dolutegravir
  • 0 views
  • 25 Mar, 2022
  • 1 location
Prognosis of Paroxysmal Kinesigenic Choreoathetosis in Korea

The aim of this study is to assess the prognosis of paroxysmal kinesigenic choreoathetosis (PKC) in Korean.

  • 0 views
  • 12 Feb, 2022
Population Pharmacokinetics of Antiepileptic in Pediatrics

The purpose of this study is to develop population pharmacokinetic models for antiepileptic drugs in a pediatric population. The interest of these models is multiple: describe the pharmacokinetics of these molecules in children and explain the inter-individual variability of concentrations through covariates such as weight, age, co-treatments, genetic polymorphisms and …

antiepileptics
levetiracetam
lacosamide
carbamazepine
cannabidiol
  • 21 views
  • 25 Jan, 2021
  • 1 location