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Found 890 clinical trials
Translating Research Into Practice

The TRIP Project aims to overcome barriers to widespread implementation and dissemination of evidence-based practices that will improve the delivery of guideline-concordant care to vulnerable women with breast cancer. To accomplish this goal the study team will create (a) regional patient registries; (b) systematic screening for social barriers to care …

  • 1 views
  • 27 Jan, 2021
  • 2 locations
Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer

This study evaluates whether sequential neo-adjuvant chemotherapy plus surgery followed by Capecitabine could achieve additional benefits over traditional postoperative chemotherapy. In the study group, patients that do not achieve pathological complete response(pCR) will receive sequential neo-adjuvant chemotherapy followed by Capecitabine. In the control group, patients will be treated with postoperative …

breast cancer
capecitabine
renal function
carcinoma
cancer
  • 0 views
  • 21 Jan, 2021
  • 1 location
Breast Cancer Toxicity

The aims of the cohort will be to quantify impact of cancer treatments toxicities , and to generate predictors of chronic toxicity in patients with non-metastatic breast cancer. The project will include four specific aims : To develop a database of chronic treatment related toxicity in a cohort of 13250 …

  • 0 views
  • 18 Mar, 2021
  • 1 location
IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment

RATIONALE: Using small radiation beamlets of different intensity, IMRT (intensity modulated radiation therapy) allows shaping the dose around planning target volume with better sparing of normal tissue comparing to 3D conformal radiotherapy. It allows daily delivery of higher dose to the tumor with simultaneous integrated boost (SIB), consequently shortening total …

primary tumor
renal function
cancer
adenocarcinoma
platelet count
  • 3 views
  • 08 Nov, 2020
  • 1 location
Decision Navigation for Advanced Prostate Cancer Treatment Options Using mHealth

team delivered interactive mHealth decision aid for patients with advanced prostate cancer to help facilitate informed shared decisions about anti-cancer treatment that affects their quality of life

  • 2 views
  • 26 Jan, 2021
  • 3 locations
PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA

The purpose of this study is to assess the strategy in treatment selection using ctDNA fraction as a predictive biomarker to direct treatment decision (ctDNA fraction <2% receives enzalutamide, and ctDNA fraction 2% receives docetaxel) versus clinician's choice of enzalutamide or docetaxel, in subjects with metastatic castration-resistant prostate cancer post …

gilbert's syndrome
progressive disease
conjugated bilirubin
adenocarcinoma
platelet count
  • 0 views
  • 23 Mar, 2021
  • 5 locations
Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients

INDICATION: Oligometastatic hormone-sensitive prostate cancer patients. METHODOLOGY: Open label, double arm, randomized 1:1, multicenter phase III study. PRIMARY OBJECTIVE: To assess the efficacy of ablative radiotherapy (SBRT applied to all oligometastases) administered to all gross tumor sites (metastases and prostate if applicable), in oligometastatic hormone-sensitive prostate cancer patients.

  • 0 views
  • 25 Jan, 2021
  • 21 locations
Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

The purpose of this study is to evaluate whether DB-020 administered via an injection in the middle ear prevents hearing loss in participants who will receive high doses of cisplatin as part of their treatment for cancer.

  • 0 views
  • 14 Mar, 2021
  • 13 locations
TO DEVELOP AND IMPLEMENT A METHOD FOR MEDICAL PREVENTION OF CARDIOVASCULAR DISEASES CAUSED BY COMPLEX TREATMENT OF PATIENTS WITH PRIMARY OPERATED BREAST CANCER

Purpose of the study: to develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

  • 0 views
  • 25 Jan, 2021
  • 1 location
Exercise and Tumor Blood Flow

could plausibly increase the efficacy of cancer treatment.

  • 0 views
  • 18 Feb, 2021
  • 1 location