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Found 241 clinical trials
Adjuvant Low Dose Aspirin in Colorectal Cancer (ALASCCA)

ALASCCA is a randomized, parallel group, double blind, multicenter, placebo-controlled, biomarker-based study of adjuvant treatment with low dose aspirin in patients with colorectal cancer. Hypothesis is that patients diagnosed with colorectal cancer and somatic mutations in PI3K pathway can significantly improve survival if treated with low dose aspirin.

rectal carcinoma
aspirin
  • 29 views
  • 03 May, 2022
  • 32 locations
Robot-assisted Approach to Cervical Cancer (RACC)

The purpose of the RACC trial is to compare the oncologic outcome defined as recurrence-free survival (RFS) between robot-assisted and open radical hysterectomy for the treatment of early stage cervical cancer.

carcinoma
cervical carcinoma
cervical cancer stage
cancer
diagnostic procedures
  • 10 views
  • 19 Apr, 2022
  • 1 location
Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesia (CAN)

The purpose of this study is to determine whether anesthesia maintained with propofol results in better one- and five-year-survival than anesthesia maintained with sevoflurane.

cancer surgery
general anesthesia
immunostimulant
cancer
sevoflurane
  • 30 views
  • 05 Jun, 2022
  • 14 locations
Sentinel Lymph Node Biopsy Versus Pelvic Lymphadenectomy in Early-stage Cervical Cancer (PHENIX/CSEM 010)

The diagnostic value of sentinel lymph node biopsy in early-stage cervical cancer has been well studied. However, there were no randomized controlled study on comparing the long-term outcomes of sentinel lymph node biopsy and conventional procedure. The investigators perform a phase III, randomized controlled trial to determine whether pelvic lymphadenectomy …

carcinoma
cervical carcinoma
cervical cancer stage
adenocarcinoma
lymphadenectomy
  • 3 views
  • 24 Jan, 2021
  • 1 location
Neoadjuvant Treatment Modalities in Esophageal Cancer

Esophageal cancer is the most prevalent cancer globally with poor survival outcome. The prognosis with surgery alone is poor, accounting for 30-40% of overall survival at 5 year. Either neoadjuvant chemotherapy (nCT) or chemoradiotherapy (nCRT) has been shown as efficatious therapy to improve patients outcomes in esophageal or esophagogastric junction …

  • 0 views
  • 06 Apr, 2021
  • 1 location
Comparison of Sublobar Resection and Lobectomy to Treat Lung Cancer

A multi-center prospective randomized trial in Taiwan to investigate whether sublobar resection, as compared to lobectomy, can offer equivalent clinical results to treat early non-small cell lung cancer.

lung carcinoma
lung cancer
cancer
metastasis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty

The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.

  • 0 views
  • 22 Mar, 2022
  • 1 location
Surveillance AFter Extremity Tumor surgerY (SAFETY)

Following treatment for a primary extremity sarcoma, patients remain at risk for the development of local and systemic disease recurrence. Metastasis (distant recurrence) to the lung is the most frequent single location of disease recurrence in sarcoma patients, occurring in almost half of all patients. Therefore, careful post-operative surveillance is …

chest ct
sarcoma of the extremity
cancer chemotherapy
primary extremity sarcoma
immunomodulators
  • 0 views
  • 27 Feb, 2022
  • 10 locations
Image Guided Penile Cancer Surgery (GLANS)

The main treatment modality for Penile Squamous Cell Carcinoma (PSCC) is surgery with curative intent. In organ sparing surgery a tumor-positive margin of up to 36% exist. Tumor-positive surgical margins are an independent risk factor for local recurrence, which has been reported to be up to 18%. Tumor-positive margins always …

  • 0 views
  • 30 May, 2022
  • 1 location
Prehabilitation for Breast Cancer Surgery

Prehabilitation for women diagnosed with breast cancer is commonly not part of the clinical pathways as little time (usually a few days) is left between diagnosis and surgery. However, a great proportion of these patients will undergo neoadjuvant chemotherapy which provides a window opportunity to improve patients' physical status to …

  • 0 views
  • 23 Mar, 2022
  • 1 location