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Found 247 clinical trials
Evaluation of Treatment Efficacy by Circulating Tumor Cell Phenotype Surveillance in Breast Cancer Patients

, primary tumor surgery with/without adjuvant chemotherapy. The aim of this observational study is to assess the efficacy of CTCs surveillance in predicting the prognosis of breast cancer patients.

tumor cells
adjuvant chemotherapy
breast cancer staging
  • 01 May, 2022
  • 1 location
Effects of Anesthetic Techniques on Time to Start of Adjuvant Chemotherapy, and Early and Late Outcomes Following Surgery for Colorectal Cancer (ENCORE)

the perioperative management of patients undergoing open, colorectal cancer surgery. Not only does it reduce pain and stress, epidurals have been shown to reduce perioperative inflammation and

intravenous anesthesia
chemotherapy regimen
  • 25 Mar, 2022
  • 1 location
Patient Experiences With the COVID-19 Vaccination After Breast Cancer Treatment (LymphVAX)

This study aims to elicit patient experiences, choices, and side effects associated with the COVID-19 vaccine after breast cancer surgery. Lymph node swelling is a known and common side effect

sentinel lymph node biopsy
cancer treatment
breast cancer
  • 21 Apr, 2022
  • 1 location
Sleep Disorders in Patients With Suspected Lung Cancer Before and After Thoracic Surgery

The main aim of this study is to prospectively evaluate the occurrence of sleep disorders in patients undergoing thoracic surgery due to the preliminary diagnosis of lung cancer. Secondary aims include anxiety, depressive mood and functional outcomes before and 3 months after the intervention.

thoracic surgery
lung carcinoma
lung cancer
  • 06 May, 2022
  • 1 location
Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

This study looks at the level of circulating tumor elements (cancer cells or DNA pieces floating in the blood) and how it may be related to how the tumor responds to standard treatment in patients with rectal cancer that has spread to nearby tissue or lymph nodes (locally advanced). Researchers …

  • 08 Apr, 2021
  • 2 locations
Atrial Fibrillation After Surgery for Colorectal Cancer

This study will report the incidence of atrial fibrillation after elective colorectal cancer resection in the over 65 age group. This will be used to validate a risk model for the development of post-operative atrial fibrillation. Eligible patients will undergo electrocardiogram based screening for atrial fibrillation, as well as brain …

  • 15 Oct, 2021
  • 1 location
Cerebellar Mutism Syndrome Study

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.

  • 28 Jan, 2021
  • 28 locations
Examining and Comparing the Temporal Changes and Results of Cosmetic, Quality of Life and Patient Satisfaction Achieved With Immediate and Delayed-immediate Implant-based Breast Reconstruction Procedures and Contralateral Symmetrization Techniques

This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of life and patient satisfaction after breast reconstructive surgery with silicone implant (following SSM, ASM or NSM …

Accepts healthy volunteers
endocrine therapy
hormone therapy
breast reconstruction
  • 04 Mar, 2022
A Multicenter Non-Interventional Cohort Study to Evaluate the Real-World Clinical Management and Outcomes of Patients Diagnosed With ALK-Positive Advanced NSCLC Treated With Alectinib (ReAlec) (ReAlec)

This study aims to characterize the clinical management and outcomes of participants diagnosed with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) who are being treated with alectinib in real-world clinical practice.

lung carcinoma
  • 23 Oct, 2022
  • 113 locations
Future of Colorectal Cancer Surgery (FOCCuS1)

Colorectal cancer is the third most common cancer in the UK and Ireland, it is the second commonest cancer in both men and women. Very often the diagnosis is made by either endoscopy/colonoscopy and the surgical treatment is carried out by a minimally invasive approach ("Keyhole"surgery). Tissue samples gathered by …

rectal carcinoma
cancer surgery
colorectal surgery
  • 23 Feb, 2022
  • 1 location