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Found 105 clinical trials
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease the rate of disease progression and improve the survival outcome of patients with unresectable locally recurrent nasopharyngeal carcinoma compared with those treated with concurrent chemo-radiotherapy alone.

karnofsky performance status
measurable disease
toripalimab
chemotherapy regimen
nasopharyngeal carcinoma
  • 0 views
  • 25 Jan, 2021
  • 6 locations
Immunotherapy for Recurrent Cervical Cancer Refractory to Platinum-based Chemotherapy: Multi-Center Trial

This is a updated trial of NCT04188860 as a multi-center study. For recurrent or persistent advanced cervical cancer patients, the first-line chemotherapy was based on platinum. However, if they were refractory to platinum-based chemotherapy, there were no other more effective medications or treatment. The marketing of anti-PD-1 antibody has provided …

measurable disease
chemotherapy regimen
treatment regimen
camrelizumab
cancer
  • 0 views
  • 11 Apr, 2022
  • 1 location
Donafenib for Recurrent Cervical Cancer

This study is to evaluate the safety and tolerability of Donafenib combined with paclitaxel and platinum ± programmed death 1 monoclonal antibody (PD-1 antibody) in patients with recurrent cervical cancer.

metastasis
measurable disease
absolute neutrophil count
creatinine clearance rate
cancer
  • 0 views
  • 19 Apr, 2022
  • 1 location
Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy (OralAcu)

This randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing chemotherapy.

taxane
chemotherapy regimen
breast cancer
primary cancer
cancer
  • 10 views
  • 30 May, 2022
  • 1 location
Patient Reported Scale vs CTCAE Grading: A Prospective Comparator Study (PROSE)

be prevented or detected early and treated. Most of the patients experience toxicity during cancer chemotherapy but the reporting remains inadequate as patients are not aware how to report or the

cancer
  • 0 views
  • 25 Mar, 2022
  • 1 location
Niraparib Plus Anlotinib for Recurrent Ovarian Cancer

This is a phase II trial to explore efficacy and safety of niraparib in combination with anlotinib based on CA 125 level in newly diagnosed ovarian cancer. After completion of 1st-line platinum-based chemotherapy with a normal CA-125 concentration, in patients with CA-125 increased > 35U/ml, and with no evidence of …

neuropathy
chemotherapy regimen
niraparib
neutrophil count
cancer of the ovary
  • 0 views
  • 29 Apr, 2022
  • 1 location
Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas

cause obvious and serious delayed damage, such as cognitive impairment, endocrine disorders, cerebrovascular events, and second tumors. Chemotherapy can effectively treat LGGs in children, and can

  • 0 views
  • 22 Mar, 2022
  • 1 location
Granisetron Transdermal Patch System for Prevention of CINV by CapeOX

This study aims to explore the prevention of delayed chemotherapy induced by CAPOX regimen with granisetron transdermal patch。

  • 0 views
  • 04 May, 2022
  • 1 location
Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

Einstein Medical Center in Philadelphia serves a diverse group of the patient population. The majority of patients have a diverse cultural background, low literacy, and poor social-economic status. Medication adherence for chronic medical problems is in a range of 40-70%. Medication adherence among patients on oral anti-cancer therapy is not …

lung cancer
antineoplastic agents
breast cancer
multiple myeloma
leukemia
  • 4 views
  • 04 Mar, 2022
  • 1 location
Impact of Home-based Aerobic and Strength Exercises During Chemotherapy for Early Breast Cancer on Biomarkers of Aging

Purpose: To determine if engagement in physical activity during chemotherapy will have a moderating effect on increases in p16 levels during chemotherapy. Participants: 100 patients age 21-64 with a Stage I-III breast cancer diagnosis who are about to start adjuvant or neoadjuvant chemotherapy. Procedures: The study entails screening, recruiting and …

breast carcinoma
immunostimulant
adjuvant chemotherapy
erbb2
  • 41 views
  • 14 Apr, 2022
  • 1 location