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Found 671 clinical trials
Breast Cancer BRCA1 Carriers: a Pilot Study

The purpose of this study is to examine how a single dose of MIFEPREX® (mifepristone) affects the breast tissue in patients with BRCA1 (a gene that normally acts to restrain the growth of cells in the breast, but if it mutates may lead to breast cancer) mutations undergoing a planned …

  • 0 views
  • 15 Jun, 2022
  • 2 locations
Mass Response of Malignant Fluid Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using isolated tumor cells from malignant fluids such as pleural effusions and ascites.

combinations
carcinoma
tumor cells
ascites
pleural effusion
  • 2 views
  • 22 Oct, 2022
  • 1 location
Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinical Characterization (PELVIMASS2)

adapted to this biology is currently in full development. For example, sequencing ovarian tumors can select patients who can benefit from anti-PARP therapy. There is therefore a need for patients to have

cancer
endometriosis
ovarian cancer
  • 2 views
  • 12 Feb, 2022
  • 2 locations
Pilot Feasibility Study of Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

The goals of this prospective, observational cohort study are to determine the feasibility of implementing paclitaxel therapeutic drug monitoring for cancer patients and explore the relationship between paclitaxel drug exposure and the development of neuropathic symptoms. This trial studies if paclitaxel can be consistently measured in the blood of patients …

lung cancer
trastuzumab
carcinoma
pembrolizumab
atezolizumab
  • 0 views
  • 18 Oct, 2022
  • 1 location
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs

The primary objective of this study, sponsored by Travera LLC in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using isolated tumor cells from varying cancers and biopsy formats. Cohorts include patients with stage III or …

lung cancer
combinations
breast cancer
carcinoma
tumor cells
  • 0 views
  • 20 Oct, 2022
  • 1 location
Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

This study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This trial may show whether at-home monitoring programs can improve the care of …

cancer
cancer treatment
primary cancer
cancer care
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Electrochemotherapy of Gynecological Cancers

To determine the effectiveness, feasibility and safety of electrochemotherapy in treatment of local and/or regional recurrences of gynecological cancers with electrochemotherapy in which standard treatment options have been exhausted.

  • 0 views
  • 26 Feb, 2021
  • 1 location
Cell-free DNA Quantification for Predictive Marker of Palliative Chemotherapy

This study is design to address, as follows: correlation between fluorescence-based CFD measurements and tumor burden (primary tumor size, number of metastatic sites) fluorescence-based CFD measurements and changes are related to tumor response. Based on the results of this study, the role of fluorescence-based CFD as a predictive biomarker for …

  • 0 views
  • 23 Mar, 2022
  • 1 location
Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples

Breast cancer is the most common cancer and cause of cancer- related deaths among women, accounting for 1.67 million (25.2%) new cases and 521,907 (14.7%) deaths worldwide. The prevalence and survival rates of breast cancer differ per country. In Indonesia, majority of patients (70.9%) go to the clinic with advanced …

Accepts healthy volunteers
mammogram
  • 0 views
  • 21 Oct, 2022
  • 1 location
Molecular Genetics and Epidemiology of Pancreatic Cancer in Ashkenazi Jewish Patients

The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic …

BRCA2
BRCA1
  • 0 views
  • 16 Oct, 2022
  • 1 location