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Found 670 clinical trials
Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Based on studies of "Inherited Susceptible Genes Among Epithelial Ovarian Cancer" (NCT03015376, clinicaltrials.gov) and "Cohort Study of Universal Screening for Lynch Syndrome in Chinese

  • 18 views
  • 21 Jan, 2021
  • 1 location
Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer

This is a large, prospective, single-arm cohort study of transvaginal ultrasonographic screening for ovarian cancer in intermediate to high-risk women from Kentucky. Detection of ovarian

cancer of the ovary
breast cancer
  • 0 views
  • 27 Jul, 2021
  • 1 location
Platino-resistance in Ovarian Cancer (PlatinOv)

Prospective, monocentric study aiming to identify factors involved in platinum based-chemotherapy resistance in patients with epithelial ovarian cancer (all stages). Patients will receive

ascites
ovarian cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Study of Intra-operative Imaging in Women With Ovarian Cancer

The purpose of this study is to find out whether using the PINPOINT imaging system intra-operatively can reduce the risk of anastomotic leaks and other complications after surgery for ovarian

cancer of the ovary
peritoneal cancer
tumor debulking
fallopian tube
cytoreductive surgery
  • 0 views
  • 14 Jul, 2022
  • 7 locations
Evaluating the Performance of Morphology Index in Surgical Decision-Making for Ovarian Tumors

distinguishing benign from malignant ovarian tumors. If there is no change in the detection of true positive cases, the result will be an increase in the positive predictive value of ovarian cancer screening.

cancer of the ovary
breast cancer
  • 7 views
  • 24 Feb, 2022
  • 1 location
A Study of Tilvestamab (BGB149) in Relapsed, Platinum-resistant, High-grade Serous Ovarian Cancer (HGSOC) Participants

The primary purpose is to assess the safety and tolerability of tilvestamab following IV administration of multiple doses to participants with HGSOC who have been treated with at least 1 complete course of platinum-based chemotherapy and whose disease has relapsed with platinum resistance ([PRR]-HGSOC) and to determine the plasma pharmacokinetics …

cancer of the ovary
platinum-based chemotherapy
cancer chemotherapy
  • 27 views
  • 04 Oct, 2022
  • 9 locations
Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women

The goal of this clinical research study is to evaluate a method involving a blood test, called CA-125, that may be helpful in the early detection of ovarian cancer in women who are at low risk

cancer of the ovary
Accepts healthy volunteers
cancer antigen 125
cancer chemotherapy
  • 1609 views
  • 16 Oct, 2022
  • 11 locations
MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO) (MATAO)

high and low grade epithelial ovarian cancer (including fallopian tube and primary peritoneal cancer) and subsequent primary treatment surgery and chemotherapy. Half of the participants will receive to

letrozole
peritoneal cancer
platinum-based chemotherapy
cancer chemotherapy
cancer of the ovary
  • 13 views
  • 04 Oct, 2022
  • 25 locations
Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected.

BRCA1/2
peritoneal cancer
platinum-based chemotherapy
cancer chemotherapy
paclitaxel
  • 6 views
  • 07 Jun, 2022
  • 86 locations
A Study to Compare Two Surgical Procedures in Women With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

This trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for women with BRCA1 mutations

oophorectomy
BRCA1
hysterectomy
cancer of the ovary
fallopian tube
  • 98 views
  • 19 Jun, 2022
  • 186 locations