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Found 61 clinical trials
A Multicenter Study of Active Specific Immunotherapy With OncoVax in Patients With Stage II Colon Cancer

OncoVAX is the first cancer vaccine that both prevents cancer recurrence and addresses the diversity of cancer cells. In this pivotal randomized, multicenter Phase IIIb study in

  • 0 views
  • 21 Jan, 2021
  • 1 location
Investigator-initiated Clinical Trial (Phase II) of Cancer Vaccine "DSP-7888" for Acute Myeloid Leukemia Patients.

This study is an investigator-initiated clinical trial (Phase II) using DSP-7888 for acute myeloid leukemia patients with 1st hematological CR. DSP-7888 is a novel cocktail peptide vaccine designed to induce cytotoxic T lymphocytes that recognize WT1 peptides.

  • 0 views
  • 07 Mar, 2021
  • 1 location
Evaluation of UCPVax Plus Nivolumab as Second Line Therapy in Advanced Non Small Cell Lung Cancer

-cancer vaccine in NSCLC patients. Nivolumab (NIVO), which is an anti-PD-1 antibody, has shown promising results in 2nd line treatment for advanced NSCLC. UCPVax is a therapeutic anti

  • 0 views
  • 27 Jan, 2021
  • 7 locations
Autologous Dendritic Cells Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG

This phase I/II trials evaluates the feasibility, safety and efficacy of an individualized cancer vaccine, based on autologous, tumor-lysate loaded dendritic cells in children and adolescents

  • 0 views
  • 26 Jan, 2021
  • 3 locations
Immunotherapy of Recurrent Cervical Cancers Using Dendritic Cells (DCs)

other investigators, we propose to evaluate the potential of immunizing cancer patients with antigen-pulsed autologous dendritic cells as a cancer vaccine to treat for recurrent cervical

tumor cells
metastasis
cervical carcinoma
papilloma
cancer
  • 29 views
  • 07 Nov, 2020
  • 1 location
Neoadjuvant GMCI Plus Chemoradiation for Advanced Non-Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to evaluate Gene Mediated Cytotoxic Immunotherapy (GMCI) in combination with standard of care chemoradiation and surgery for borderline resectable and unresectable locally advanced pancreatic cancer in patients who have completed induction chemotherapy. GMCI kills tumor cells and creates an immune stimulatory environment in the …

tumor cells
neutrophil count
metastatic pancreatic adenocarcinoma
cancer
  • 0 views
  • 27 Jan, 2021
  • 5 locations
MIDRIX4-LUNG Dendritic Cell Vaccine in Patients With Metastatic Non-small Cell Lung Cancer

MIDRIX4-LUNG is a novel tetravalent autologous dendritic cell vaccine in metastatic non-small cell lung cancer patients. This first-in-human study aims to primarily establish maximal tolerated dose of MIDRIX4-LUNG administered i.v.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer

radical prostatectomy (RP) or definitive RT and no distant metastasis or locoregional recurrence. The trial is a randomized placebo-controlled double-blind study of a peptide cancer vaccine (RV001V).

prostatectomy
bone scan
metastasis
prostate adenocarcinoma
adenocarcinoma
  • 33 views
  • 07 Mar, 2021
  • 35 locations
PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy)

Open-label, multicenter, dose titration and four-arm expansion trial to evaluate the safety, tolerability, immunogenicity, and preliminary efficacy of W_pro1 cancer vaccine (W_pro1) monotherapy

serum testosterone
cancer vaccine
goserelin
cabazitaxel
gonadorelin
  • 57 views
  • 27 Jan, 2021
  • 23 locations
UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

UV1 is a therapeutic cancer vaccine that has been explored in prostate, lung cancer, in combination with ipilimumab in malignant melanoma and in combination with pembrolizumab in metastatic

direct bilirubin
metastasis
lung cancer
nivolumab
cancer
  • 0 views
  • 24 Feb, 2021
  • 28 locations