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Found 18 clinical trials
Pilot Study of Cabazitaxel and Paclitaxel in HER2 Negative Breast Cancer

90 patients with HER2 negative breast cancer will be randomised to receive 18 weeks of chemotherapy treatment, either 6 cycles of 3 weekly Cabazitaxel or 6 cycles of weekly Paclitaxel to

  • 263 views
  • 23 Jan, 2021
  • 12 locations
A Randomised Trial of Cabazitaxel Docetaxel Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients Without Metastasis

Current agents administered in therapeutic regimens of prostate cancer employ different mechanisms to eliminate neoplastic cells by inducing substantial apoptosis and causing tumor regression. Treatment with neoadjuvant chemotherapy before radical prostatectomy may better control the tumor before it has the chance to convert into the disease of castration-resistant prostate cancer …

  • 3 views
  • 26 Jan, 2021
  • 2 locations
A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.

This is a Phase II, international, open-label, two-arm, non-randomised study of AZD4635 in participants with metastatic castration-resistant prostate cancer (mCRPC).

  • 3 views
  • 20 Sep, 2021
  • 43 locations
A Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and High-risk Features of Relapse

The objective of this study is to assess the effect of neoadjuvant cabazitaxel and pelvic radiotherapy in combination with androgen deprivation therapy (ADT)-radiotherapy on clinical progression

metastasis
androgens
prostate specific antigen
androgen suppression
neutrophil count
  • 0 views
  • 26 Jan, 2021
  • 1 location
ProBio: A Biomarker Driven Study in Patients With Metastatic Castrate Resistant Prostate Cancer

Metastatic castrate resistant prostate cancer (mCRPC) is an advanced form of prostate cancer that affects 2500 - 3000 Swedish men every year. The last years, new drugs have been approved for treatment of mCRPC. Although the drugs are beneficial for many patients they carry three serious disadvantages: treatment costs are …

  • 2 views
  • 25 Jan, 2021
  • 27 locations
Docetaxel Versus Cabazitaxel Post Abiraterone or Enzalutamide

is a Phase II Study of Cabazitaxel plus prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC). The current study is designed to determine if cabazitaxel will improve

ct scan
metastasis
enzalutamide
prednisone
testosterone
  • 4 views
  • 18 Aug, 2021
  • 3 locations
CASCARA: Castration Sensitive Carboplatin Cabazitaxel and Abiraterone

treatment combination. This study will evaluate dose levels of carboplatin AUC 4 with cabazitaxel 20 mg/m2. Patients will be treated with the combination of ADT and carboplatin and cabazitaxel for 6 cycles

metastasis
orchiectomy
prednisone
neutrophil count
testosterone
  • 2 views
  • 03 Jun, 2021
  • 8 locations
Cabazitaxel Activity in Patients With Advanced AdrenoCortical-Carcinoma Progressing After Previous Chemotherapy Lines

drugs targeting the microtubules that have shown to be effective in the treatment of several malignancies but have not been fully developed in patients with ACC. Cabazitaxel is a new taxoid which

metastasis
mitotane
cytotoxic chemotherapy
cancer
neutrophil count
  • 91 views
  • 22 Jan, 2021
Cabazitaxel Carboplatin and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer

This phase II trial studies the effect of cabazitaxel, carboplatin, and cetrelimab followed by niraparib with or without cetrelimab in treating patients with aggressive variant prostate cancer

  • 0 views
  • 03 Feb, 2021
  • 1 location
Trial Evaluating the Safety of 2 Schedules of Cabazitaxel in Elderly Men With mCRPC Previously Treated With a Docetaxel

The purpose of this study is to evaluate the incidence of grade 3 neutropenia and/or neutropenic complications (febrile neutropenia, neutropenic infection) with two schedules of cabazitaxel (bi

surgical castration
prednisone
neutrophil count
progressive disease
testosterone
  • 10 views
  • 23 Jan, 2021
  • 54 locations