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Found 64 clinical trials
Featured trial
Antithymocyte Globulin (ATG) and Pegylated Granulocyte Colony Stimulating Factor (GCSF) in New Onset Type 1 Diabetes

Antithymocyte Globulin (ATG) and Pegylated Granulocyte Colony Stimulating Factor (GCSF) in New Onset Type 1 Diabetes

  • 233 views
  • 25 Mar, 2021
  • 1 location
Featured trial
CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1 Diabetes

CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1 Diabetes

  • 328 views
  • 25 Mar, 2021
  • 1 location
Effect of Metabolic Control at Onset of Diabetes on Progression of Type 1 Diabetes

The aim of this study is to determine if early and tight restoration of metabolic control at the onset of Type 1 diabetes (T1DM) will improve insulin secretion (C-peptide production

  • 182 views
  • 07 Nov, 2020
  • 3 locations
Effects of GABAA Receptor Modulation by AP-325 on Insulin Secretion in Patients With Type 2 Diabetes

on C-peptide release as measure of insulin secretion compared to placebo in type 2 diabetes (T2D) patients.

  • 0 views
  • 14 Jan, 2022
  • 1 location
Clinical Study of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Type 2 Diabetic Nephropathy

The study was a 48-week multicenter, randomized, double-blind, placebo-controlled trial that included 8 weeks of pre-screening and lifestyle education, 32 weeks of treatment, and 16 weeks of follow-up.To observe the efficacy and safety of umbilical cord mesenchymal stem cell infusion in Chinese patients with type 2 diabetic nephropathy who received …

  • 0 views
  • 27 Jan, 2021
  • 1 location
CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients

This is a Phase II/III, Single-center, Prospective, Open-label, Single Arm Study of 30 Simultaneous Kidney Pancreas recipients who received a transplant at least 3 months, but no more than 5 years prior, with a history of tremors following transplantation.

  • 1 views
  • 02 Jul, 2021
  • 1 location
Phenotypic and Genotypic Characterization of New-onset Type I Diabetes

The goal of DIATAG study is the identification of biomarkers of T1D evolution in a pediatric cohort.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism

Purpose/Objectives: To investigate the effect of hyperglucagonemia on insulin action, particularly on adipose tissue. Research Design/Plan: Normal glucose tolerant subjects will be studied. Study subjects will receive a continuous glucagon infusion for 12 hours. Following glucagon infusion, subjects will receive prime-continuous tracer infusions for additional 4 hours to measure adipocyte …

  • 3 views
  • 18 Sep, 2021
  • 2 locations
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs

Epidemiologic, social and economic burdens of type 2 diabetes mellitus (T2DM) keep rising worldwide. Implementation of T2DM preventive trategies is lagging behind. Metabolic surgery, very low calorie diet can induce T2DM remission, but so far for few patients. The investigators will assess the efficacy to cause T2DM remission (primary end …

  • 2 views
  • 23 Aug, 2021
  • 1 location
MELD-ATG: Phase II, Dose Ranging, Efficacy Study of Anti-thymocyte Globulin (ATG) Within 6 Weeks of Diagnosis of Type 1 Diabetes (T1D)

stimulated C-peptide at 12 months compared to placebo to identify the minimally effective dose of ATG that shows an effect on C-peptide when compared to placebo at 12 months

  • 0 views
  • 12 Jan, 2022
  • 6 locations