Found 102 clinical trials
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Omega Loop Gastric Bypass With And Without Anti-Reflux Sutures
This proposed trial is designed to answer the following questions: First, is biliary reflux to the distal esophagus present before OLGB and does it increase after the procedure? Second, does performing an OLGB with or without anti-reflux sutures make a difference in (biliary) reflux exposures of the distal esophagus? To …
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Ketogenic Diet and CPAP Previous Bariatric Surgery
Obstructive Sleep Apnea Syndrome (OSAS) and obesity tend to coexist and are often associated with arterial hypertension, dyslipidaemia, and insulin resistance [1]. Polysomnography (PSG) is the standard technique for diagnosing OSAS and determining its severity [2]. The results of the examination provide the Apnea-Hypopnea Index [AHI], or the Respiratory Disturbance …
- 1 views
- 27 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer
Induction chemotherapy will be administered every 2 weeks for 6 cycles (about 3 months). Patients who have radiological evidence of progressive disease will be shifted to salvage chemotherapy. Patients who have responsive or stable disease after induction chemotherapy will receive concurrent chemoradiotherapy 3-4 weeks after the last dose of induction …
- 11 views
- 07 Nov, 2020
- 2 locations
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Gastroenterology
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Currently Recruiting
Does Daily Supplementation of Lactobacillus Acidophilus MPH734 for One Week Affect Acute (Immediate) Subacute (7 Days) and Post-treatment Discontinuation Lactose Metabolism Gastrointestinal Symptoms and Clinical Markers of Inflammation and Safety Compared to a Placebo
The purpose of this study is to determine if twice or three times daily supplementation of Lactobacillus acidophilus MPH734 (Lacto-FreedomTM, or LF), for one week, affects acute (immediate), subacute (7 days), and post-treatment discontinuation (30-, 60-, and 90- day) lactose metabolism, gastrointestinal symptoms, and clinical markers of inflammation and safety …
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis
Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, …
- 12 views
- 22 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
Role of Blood Management in Perioperative Outcomes
There is currently limited information regarding the role of blood management in the benign gynecologic population and specifically, in patients who are scheduled to undergo surgery for fibroids and/or abnormal uterine bleeding. A thorough search through PubMed and clinicaltrials.gov did not reveal any studies on this issue. In 2019 at …
- 0 views
- 03 Feb, 2021
- 1 location
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pulmonary/Respiratory Diseases
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Currently Recruiting
Different Limb Lengths in Gastric Bypass Surgery
Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of co-morbidities in the majority of patients. One of the most frequently performed operations is the laparoscopic proximal …
- 0 views
- 25 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery
Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. It is now realized that intraoperative hypotension is an important risk factor for the development of AKI. In a recent randomized controlled trial of patients undergoing major noncardiac surgery, intraoperative individualized blood-pressure management …
- 0 views
- 01 Feb, 2021
- 1 location
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Multi-country trial
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery
The purpose of this study is to determine if evolocumab added to regular statin therapy improves vein graft patency after coronary artery bypass graft (CABG) surgery.
- 4 views
- 25 Jan, 2021
- 9 locations
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Randomised Controlled Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis. Given the progressive nature of coronary disease, bypass grafts can narrow or block over time, leading to chest pain and the need for further invasive coronary angiography. …
- 0 views
- 26 Jan, 2021