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Found 64 clinical trials
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes

The study is a Phase II clinical trial. Patients will receive intensity modulated total marrow irradiation (TMI) at a dose of 9 Gy with standard myeloablative fludarabine/ i.v. targeted busulfan

antithymocyte globulin
busulfan
flt3 internal tandem duplication
fludarabine
hla-a
  • 6 views
  • 30 Jun, 2022
  • 1 location
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

The purpose of this study is to determine whether the use of lower doses of busulfan and the elimination of cyclosporine will further reduce transplant-related side effects for patients with

leukemia
colony stimulating factor
busulfan
granulocyte colony stimulating factor
filgrastim
  • 76 views
  • 21 Apr, 2022
  • 2 locations
Romidepsin Maintenance After Allogeneic Stem Cell Transplantation

The goal of this clinical research study is to learn if giving romidepsin before and after a stem cell transplant in combination with fludarabine and busulfan can help to control leukemia or

leukemia
lymphocytic leukemia
lymphoid leukemia
lymphoma
fludarabine
  • 122 views
  • 03 May, 2022
  • 1 location
Aza-Ven Followed by Reduced Toxicity Conditioning Regimen (MBF) as Salvage Therapy for Refractory AML.

of Fludarabine + Busulfan + Melphalan as salvage treatment in patients with refractory AML .

  • 0 views
  • 09 Jun, 2021
  • 3 locations
Decitabine Plus mBU/CY Preconditioning for Relapse/Refractory Acute Leukemia

demonstrated efficacy in the treatment of patients with recurrent or refractory leukemia and myelodysplastic syndrome. It was reported that the combination of decitabine, with busulfan and cyclophosphamide as

cell transplantation
acute leukemia
cyclophosphamide
busulfan
remission
  • 1 views
  • 09 Feb, 2022
  • 1 location
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

This is a Phase II study of allogeneic hematopoietic stem cell transplant (HCT) using a myeloablative preparative regimen (of either total body irradiation (TBI); or, fludarabine/busulfan for

leukemia
consolidation therapy
myeloid leukemia
minimal residual disease
b-cell lymphoma
  • 58 views
  • 06 May, 2022
  • 1 location
Clofarabine Pre-conditioning Followed by Hematopoietic Stem Cell Transplant With Post-Transplant Cyclophosphamide for Non-remission Acute Myeloid Leukemia

, Busulfan (2 doses) or cyclophosphamide (2 doses) and Total Body Irradiation (TBI) with post transplant cyclophosphamide for patients with Acute Myeloid Leukemia (AML) who are not in remission prior to

total body irradiation
induction chemotherapy
colony stimulating factor
clofarabine
transplant conditioning
  • 0 views
  • 18 Oct, 2022
  • 1 location
Allogeneic Stem Cell Transplantation in Relapsed/Refractory T-, NK/T-cell Lymphomas (RRTCLAlloSCT)

trial is studying the efficacy and safety of busulfan plus fludarabine as conditioning therapy followed by allogeneic stem cell transplantation (Allo-SCT) in T- and NK/T-cell lymphoma patients who have

angioimmunoblastic t-cell lymphoma
large cell lymphoma
autograft
fludarabine
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

This is a standard of care treatment guideline for high risk or relapsed solid tumors or CNS tumors consisting of a busulfan, melphalan, thiotepa conditioning (for solid tumors) or carboplatin

atypical teratoid/rhabdoid tumor
mg++
karnofsky performance status
paclitaxel
complete resection
  • 209 views
  • 04 May, 2022
  • 1 location
ChiCGB vs BEAM in High-risk or R/R Lymphomas

combined with cladribine, gemcitabine, and busulfan (ChiCGB) as conditioning therapy improved the survival of these patients. So we designed this trial to verify if ChiCGB were better than BCNU, etoposide

ejection fraction
carbon monoxide
etoposide
renal function
stem cell transplantation
  • 0 views
  • 04 Oct, 2022
  • 7 locations