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Found 28 clinical trials
Featured trial
A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease

A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease

  • 143 views
  • 25 Mar, 2021
  • 1 location
A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV

Many people living with HIV (PLWH) smoke. Smoking in these individuals is often undertreated. This study plans to assess the ability of various clinical pathways involving tobacco treatment medications and contingency management (paying smokers for not smoking) to improve smoking cessation in a group of PLWH.

  • 0 views
  • 01 Sep, 2021
  • 3 locations
Bupropion for the Prevention of Postpartum Smoking Relapse

postpartum. Participants will be randomized to receive extended-release bupropion (active 300mg or placebo once daily beginning 4 to 10 days postpartum to 12 weeks post-randomization). All participants will

  • 0 views
  • 11 Jul, 2021
  • 1 location
Nicotine Replacement Therapy Counseling Varenicline and Bupropion for Smoking Cessation the PISCES I Trial

replacement therapy, counseling, and/or drugs such as varenicline and bupropion may help participants quit smoking or change smoking behavior. This trial may also help doctors individualize smoking cessation

  • 0 views
  • 26 Jan, 2021
Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

and on a CYP2B6 substrate using bupropion. The effect of multiple oral doses of the moderate cytochrome P450 (CYP) inhibitor modafinil on encorafenib in combination with binimetinib will also be

  • 37 views
  • 25 Nov, 2021
  • 88 locations
Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers a Pragmatic Randomised Controlled Trial

Objective: Our study aims to evaluate the effectiveness of the "STOP" (Sevrage Tabagique l'aide d'Outils ddis selon la Prfrence: Smoking Cessation using preference-based tools) intervention, a preference-based smoking cessation intervention for smokers with low socio-economic position (SEP). Methods : STOP is a randomised, multi-centre, single blinded, intent-to-treat trial. Participating centres …

nicotine replacement
bupropion
addiction
motivational interviewing
carbon monoxide
  • 0 views
  • 22 May, 2021
  • 15 locations
Varenicline and Bupropion for Alcohol Use Disorder

The COMB study is a randomized double-blind placebo-controlled multicenter trial in Sweden on the efficacy of varenicline and bupropion, in combination and alone, for treatment of alcohol use

bupropion
alcohol use disorder
  • 10 views
  • 23 Jan, 2021
  • 10 locations
Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder

This study will test the efficacy of naltrexone HCI and bupropion HCI (NB) versus placebo in patients with binge-eating disorder (BED), with or without obesity.

bulimia
naltrexone
bupropion
psychiatric disorder
  • 269 views
  • 22 Jul, 2021
  • 1 location
Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits

This study is designed to determine whether bupropion (vs escitalopram) increases functional connectivity (FC) within reward-related neurocircuits and decreases motivational deficits in

fluoxetine
depressed mood
scid
antidepressants
psychotropic drugs
  • 0 views
  • 17 Jan, 2022
  • 1 location
Bupropion in Reducing Cancer Related Fatigue in Stage I-III Breast Cancer Survivors

This phase III trial studies how well bupropion works in reducing cancer related fatigue in stage I-III breast cancer survivors. Bupropion is a drug that is used to treat depression, as well as

cancer
bupropion
  • 171 views
  • 17 Nov, 2021
  • 179 locations