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Found 102 clinical trials
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Study Seeking Patients with Opioid Use Disorder

Study Seeking Patients with Opioid Use Disorder

  • 25 Mar, 2021
  • 1 location
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (VA-BRAVE)

VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous (in the belly area) formulation of buprenorphine at a target dose of 300mg is superior in retaining Veterans in

  • 17 Jun, 2022
  • 18 locations
Emergency Department-Initiated Buprenorphine Validation Network Trial

-initiated buprenorphine (BUP) for patients presenting with opioid use disorder (OUD) who are not receiving medications for opioid use disorder (MOUD). Once implementation is adequately achieved, the sites

  • 16 Sep, 2021
  • 37 locations
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

This is a multi-centre, open-label RCT at four Emergency Departments (EDs) in British Columbia and Alberta. The purpose of the current study is to compare the effectiveness of buprenorphine

  • 10 Aug, 2021
  • 4 locations
Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

strategies for improving retention on buprenorphine (BUP) and extended-release injectable naltrexone (XR-NTX). The Discontinuation Phase will assess which approaches are most likely to lead to long-term

  • 30 Jun, 2022
  • 19 locations
Smartphones for Opiate Addiction Recovery (SOAR)

Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major NIDA policy goal. The 5-minute battery indicates the numerical probability that a patient will …

  • 20 Jun, 2022
  • 1 location
Kentucky Women's Justice Community Opioid Innovation Network (W-JCOIN)

This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and maintenance in the community following jail release. This trial will focus on incarcerated women in 6 experimental and 3 control sites in Kentucky. …

Accepts healthy volunteers
  • 11 Mar, 2022
  • 7 locations
Counseling for Office-Based Buprenorphine

The major goal is to determine whether adding cognitive behavioral therapy to physician management will increase the efficacy of buprenorphine/naloxone treatment in an office-based

drug use
  • 07 Nov, 2020
  • 1 location
Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder

The study is 12-week, randomized, open-label study comparing injectable extended-release buprenorphine (Sublocade) to standard therapy (sublingual buprenorphine), to see if Sublocade will be

  • 07 Aug, 2021
  • 1 location
Buprenorphine Loading in the Emergency Department

Buprenorphine (BUP) is FDA-approved for the treatment of opioid withdrawal and opioid use disorder. Few ED providers have received the necessary DEA registration (aka X waiver) required to

  • 25 Mar, 2022
  • 1 location