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Found 148 clinical trials
Effects of Electronic Cigarette Use on the Lungs

This randomized pilot clinical trial studies the effects of electronic cigarettes on the lungs. Studying the effects of electronic cigarettes on the lungs may provide the Food and Drug Administration (FDA) and other government regulators with important information, which may help in developing future regulations to make electronic cigarettes safer.

cotinine
tobacco smoke
smoke tobacco
medication treatment
nicotine product
  • 63 views
  • 04 Oct, 2022
  • 1 location
Obesity Metabolic Dysregulation and the Airway Epithelium in Asthmatics

The objective of this pilot study is to determine whether obesity and metabolic syndrome are in fact synergistic in relation to airway nitric oxide (NO) biology. To do so, the investigators want to determine how obesity and the metabolic syndrome relate to metabolism in bronchial airway epithelial cells and the …

asthma
a 12
albuterol
metabolic syndrome
serum hdl cholesterol
  • 85 views
  • 30 Sep, 2021
  • 1 location
RheOx Registry Study in Europe

Post-market clinical study (registry study) to collect post-market safety and clinical utility data in European patients with chronic bronchitis treated with RheOx.

bronchitis
  • 3 views
  • 13 Apr, 2022
  • 2 locations
Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Advanced Non-small Cell Lung Cancer

The purpose of this study is to evaluate the relevance of intratumoral washing for detection of EGFR mutation (including T790M positivity).

erlotinib
endobronchial ultrasound
liquid biopsy
EGFR
afatinib
  • 0 views
  • 28 Oct, 2022
  • 1 location
Assessing the Expression and the Activity of Rac1 Protein in the Airway Smooth Muscle of Asthmatic Patient (NaRacAS)

Asthma is a chronic inflammatory respiratory disease affecting 6 to 7% of the French adult population and responsible of 1000 deaths in France every year. Many anti-inflammatory treatments are available but few had been developed to target hyperresponsiveness.Investigators and searchers of the Institut du thorax have recently demonstrated the main …

wheezing
bronchodilator
respiratory disorder
dust mite
cough
  • 0 views
  • 08 Feb, 2022
  • 1 location
Endobronchial Ultrasound-Guided Transbronchial Needle-Aspiration With Suction in Obtaining Samples From Patients With Suspected Nodal Metastatic Lung Cancer

This trial studies how well endobronchial ultrasound-guided transbronchial needle-aspiration (EBUS-TBNA) with suction works in obtaining samples from patients with suspected lung cancer that has spread to the nodal. EBUS-TBNA samples obtained with additional suction may help to improve material-amounts and decrease blood contamination in the samples.

endobronchial ultrasonography
tbna
lung cancer
bronchoscopy
cancer
  • 0 views
  • 03 Jul, 2022
  • 1 location
The Lung PCA: A Multi-Dimensional Atlas of Pulmonary Premalignancy

This protocol pertains specifically to the prospective lung squamous cell carcinoma pre-malignant lesion (PML) cohort that will form a primary study group for the Lung Pre-Cancer Atlas.

carcinoma
lung cancer
withdrawn
cancer
lung carcinoma
  • 0 views
  • 18 Feb, 2022
  • 2 locations
Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients

This study is being done to study a safe and non-invasive way to diagnose lung rejection and infection.

Accepts healthy volunteers
  • 0 views
  • 05 Jul, 2022
  • 1 location
Evaluation of the NOVATECH ® LUCIOLA TM EB Fiducial Marker During Radiotherapy Sessions in Lung Cancer Patients

Following CE certification, this Post Market Clinical Follow-up investigates the performance and safety of using the new fiducial marker, NOVATECH® LUCIOLA™ EB, in the lung airways to monitor in real-time tumor location during radiotherapy. At the time of insertion near the tumor, the Luciola's 3 fiducial marker arms are deployed …

lung cancer
cancer
lung carcinoma
  • 0 views
  • 29 Dec, 2021
  • 8 locations
Project 2 Airway Potential Hydrogen (pH) in Asthma

This study is testing a non invasive way to measure airway pH in individuals with Asthma and Cystic Fibrosis using a new inhaled drug. The airway pH will help health care providers in creating tailored treatment plans for individuals suffering from these specific conditions.

pulmonary disease
methacholine challenge
asthma
pilocarpine
acute asthma
  • 189 views
  • 11 Mar, 2022
  • 2 locations