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Found 54 clinical trials
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A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Brodalumab in Subjects With Inadequately Controlled Asthma and High Bronchodilator Reversibility.

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Brodalumab in Subjects With Inadequately Controlled Asthma and High Bronchodilator Reversibility.

  • 72 views
  • 23 Nov, 2020
  • 1 location
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A Phase II, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lebrikizumab in Patients with Chronic Obstructive Pulmonary Disease and a History of Exacerbations

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lebrikizumab in Patients with Chronic Obstructive Pulmonary Disease and a History of Exacerbations

  • 242 views
  • 25 Mar, 2021
  • 1 location
A Pilot Efficacy Study of Inhaled Albuterol Delivered With Akita Breath Control

of the standard nebulized dose of albuterol will be required to attain same bronchodilator response as a standard nebulizer treatment as determined by lung function measurement and that the

pulmonary function test
bronchodilator
albuterol
  • 74 views
  • 07 Nov, 2020
  • 1 location
Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.

To determine the efficacy of nebulized 5% hypertonic saline on cough severity and quality of life, in children with non-CF CSLD. Secondary Aims: To determine the: Efficacy of nebulized 5% hypertonic saline on airway microbiome, pulmonary exacerbation rate, healthcare utilization, and rescue antibiotics. Efficacy of nebulized 5% hypertonic saline on …

  • 0 views
  • 02 Mar, 2021
  • 1 location
Feasibility Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPD

The purpose of this study is to assess the feasibility, safety and efficacy of a combination of nebulized Formoterol and Revefenacin among patients hospitalized for AECOPD compared with standard-of-care therapy with nebulized Albuterol and Ipratropium.

  • 0 views
  • 09 May, 2021
  • 1 location
Longitudinal 3He Magnetic Resonance Imaging of Healthy Lung

Healthy elderly subjects male and female aged 65-85 will undergo MRI, lung function and exercise testing for the development of tools to quantify and validate longitudinal in vivo magnetic resonance imaging phenotypes of the aging lung.

  • 2 views
  • 23 Jan, 2021
  • 1 location
Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study)

The investigators aim to assess the safety and efficacy of nebulized liposomal amphotericin B (ALN) as a complementary therapy to the usual systemic treatment in patients with invasive pulmonary aspergillosis and the utility of a non-routine test as a surrogate marker of efficacy. To this end, a 3-year phase I, …

  • 6 views
  • 13 Feb, 2021
  • 1 location
Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial

Large population-based studies suggest that patients with chronic obstructive pulmonary disease (COPD) are 2 to 3 times at risk for cardiovascular mortality, which accounts for a large proportion of the total number of deaths. How COPD increases the risk of poor cardiovascular outcomes is largely unknown. However, there is growing …

fluticasone
bronchodilator
corticosteroids
cigarette smoke
  • 130 views
  • 07 Nov, 2020
  • 9 locations
Roflumilast in Non-CF Bronchiectasis Study (2019)

This is a single-arm, open label, Phase II study of 12-week use of Roflumilast in stable-state non-cystic fibrosis bronchiectasis subjects. Bronchiectasis refers to a suppurative lung condition characterized by pathological dilatation of bronchi. The predominant aetiology of bronchiectasis in the Western population is related to cystic fibrosis (CF), which is …

  • 0 views
  • 10 May, 2021
  • 1 location
SOLIDARITY Finland Long COVID-19

The primary aim of the SOLIDARITY Finland Long-COVID trial is to assess the long-term effects of remdesivir use during hospitalisation on long-COVID symptoms and quality of life (QoL) using questionnaires at one and two years post-discharge. The primary research questions are whether remdesivir lowers the risk of long-COVID symptoms and …

  • 0 views
  • 01 Aug, 2021
  • 1 location