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Found 54 clinical trials
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A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Brodalumab in Subjects With Inadequately Controlled Asthma and High Bronchodilator Reversibility.

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Brodalumab in Subjects With Inadequately Controlled Asthma and High Bronchodilator Reversibility.

  • 72 views
  • 23 Nov, 2020
  • 1 location
Formoterol-beclomethasone in Patients With Bronchiectasis: a Randomized Controlled Trial (FORZA)

Randomized, double-blind, placebo-controlled study comparing formoterol-beclometason 12/200 mcg BID versus placebo to evaluate the clinical effect on coughing in patients with non-cystic fibrosis (non-CF) bronchiectasis, native to inhaled corticosteroid (ICS) therapy and no history of asthma or chronic obstructive pulmonary disease (COPD)

cystic fibrosis
beclomethasone
cough
asthma
high resolution computed tomography
  • 0 views
  • 10 Apr, 2022
  • 3 locations
Evaluate the Efficacy and Safety of FB704A in Adult With Severe Asthma

This is a randomized, placebo controlled and double blind study to evaluate the safety, tolerability, pharmacokinetics, and clinical activity of FB704A in adult patients with severe asthma. The study comprised a 4-week screening period, a 8-week treatment period and a 12-week follow-up period.

  • 0 views
  • 07 Apr, 2022
  • 4 locations
Normal Saline Nebulization on Prevention of Extubation Failure in Neonates

this study is about evaluating the effect of using normal saline nebulization in preventing re-intubation in extubated neonates , provided that the cause of intubation is mainly due to respiratory cause

  • 0 views
  • 26 Mar, 2022
  • 1 location
Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.

To determine the efficacy of nebulized 5% hypertonic saline on cough severity and quality of life, in children with non-CF CSLD. Secondary Aims: To determine the: Efficacy of nebulized 5% hypertonic saline on airway microbiome, pulmonary exacerbation rate, healthcare utilization, and rescue antibiotics. Efficacy of nebulized 5% hypertonic saline on …

  • 0 views
  • 24 May, 2022
  • 1 location
Longitudinal 3He Magnetic Resonance Imaging of Healthy Lung

Healthy elderly subjects male and female aged 65-85 will undergo MRI, lung function and exercise testing for the development of tools to quantify and validate longitudinal in vivo magnetic resonance imaging phenotypes of the aging lung.

  • 14 views
  • 23 Jan, 2021
  • 1 location
Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study) (NAIFI01)

The investigators aim to assess the safety and efficacy of nebulized liposomal amphotericin B (ALN) as a complementary therapy to the usual systemic treatment in patients with invasive pulmonary aspergillosis and the utility of a non-routine test as a surrogate marker of efficacy. To this end, a 3-year phase I, …

  • 38 views
  • 27 Feb, 2022
  • 1 location
Evaluate the Efficacy and Safety of FB825 in Adult With Allergic Asthma

This is a randomized, placebo-controlled and double-blind study to evaluate the efficacy and safety of FB825 in adult patients with moderate-to-severe allergic asthma.

  • 0 views
  • 21 Apr, 2022
  • 4 locations
Flow Cytometry Analysis of Eosinophils in Severe Asthma Patients.

Asthma is a heterogeneous disease, characterized by reversible airflow obstruction, airway hyperresponsiveness, and airway inflammation, in which 40% of patients exhibit eosinophil-driven pathobiology.The main treatment of asthma is the use of corticosteroid, whose use induces a reduction in eosinophils that is considered a strong predictor of response to treatment. Corticosteroids …

  • 0 views
  • 21 Aug, 2021
  • 1 location
Roflumilast in Non-CF Bronchiectasis Study (2019)

This is a single-arm, open label, Phase II study of 12-week use of Roflumilast in stable-state non-cystic fibrosis bronchiectasis subjects. Bronchiectasis refers to a suppurative lung condition characterized by pathological dilatation of bronchi. The predominant aetiology of bronchiectasis in the Western population is related to cystic fibrosis (CF), which is …

  • 0 views
  • 10 May, 2021
  • 1 location