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Found 79 clinical trials
Mitochondrial Dysfunction of Alveolar and Circulating Immune Cells During Acute Respiratory Distress Syndrome: Impact of Infectious Aggression and Alveolar Stretching as a Result of Mechanical Ventilation. (PNEUMOCHONDRIE)

Sepsis leads to a deregulated host response that can lead to organ failure. During sepsis, experimental and clinical data suggest the occurrence of mitochondrial dysfunctions, particularly in circulating muscle and monocytes, which may contribute to organ failure and death. Lower respiratory infection is the leading cause of death from infectious …

respiratory distress
antibiotics
x-rays
FIO2
dyspnea
  • 0 views
  • 15 Jul, 2022
  • 1 location
Bio Metrology of Nonfibrous Mineral Particles in Bronchoalveolar Lavage Fluids (REACTIT)

The main purpose of this study is to update the pulmonary retention values of non-fibrous mineral particles in the general population. This study will provide reference values for the interpretation and diagnosis of the cause of certain respiratory diseases potentially related to mineral particles.

Accepts healthy volunteers
  • 0 views
  • 19 Jun, 2022
  • 1 location
PLAIAR-Trial: Platelets in Inflammation and Resolution

Detection and determination of platelets in bronchoalveolar lavage fluid and blood in ARDS and non-ARDS-patients. Correlation with phenotype and inflammation parameters in blood and outcome

  • 0 views
  • 19 Nov, 2021
  • 1 location
Screening Microorganism of Cryptogenic Mechanical Pneumonia Through Next Generation Sequencing to Lung Tissue Fluid

The etiology of cryptogenic organizing pneumonia (COP)was not clear, but previous studies have shown that in some patients, some pathogen could be detected in bronchoalveolar lavage fluid (BALF

  • 0 views
  • 25 Jan, 2021
  • 2 locations
A Single-cell Approach to Identify Biomarkers of Pulmonary Toxicity for Immune Checkpoint Blockade

The main goal of this prospective non-interventional exploratory monocentric study is to characterize the immune cell composition of bronchoalveolar lavage (BAL) fluid from cancer patients

  • 0 views
  • 24 Mar, 2021
  • 1 location
The Diagnosis of Superinfections in Mechanically Ventilated Covid-19 Patients

bronchoalveolar lavage fluid (BALF) for Polymerase Chain Reaction (PCR) detection of pathogens and antigenic detection of mycoses. This project can support the routine use of BALF and PCR diagnostics for

pao2
coronavirus
covid-19
SARS
mechanical ventilation
  • 0 views
  • 05 Jan, 2022
  • 1 location
Breath Condensate Study in Patients With Cystic Fibrosis.

either collecting a sputum sample or obtaining a bronchoalveolar lavage (BAL). However, some patients cannot produce sputum. At the same time the decision of when a patient has an exacerbation continues

fibrosis
Accepts healthy volunteers
  • 8 views
  • 04 Oct, 2022
  • 1 location
Characterization of Pulmonary Langerhans Cell Histiocytosis

mutations in bronchoalveolar lavage will represent a significant advance in the diagnosis and treatment of these patients. An undetermined percentage of HCL does not present mutations in B-RAF. Consequently

  • 12 views
  • 25 Jan, 2021
  • 1 location
Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes

bronchoalveolar lavage fluid (BALF) which may help differentiate the ARDS endotypes.

diagnostic procedures
acute respiratory distress
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Airway Remodeling During Mepolizumab Treatment (REMOMEPO)

airway smooth muscle (ASM) area, in the number of PGP9 sections will be assessed on bronchial biopsies after 6 months and 12 months of mepolizumab treatment. Bronchoalveolar lavage (BAL) levels of

mepolizumab
airway remodelling
  • 6 views
  • 26 Mar, 2022
  • 1 location