Found 59 clinical trials
RASopathy Biorepository
The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) pathway. New RASopathies are being diagnosed frequently. This pathway is essential in the regulation of the cell cycle and the determination of cell function. Thus, appropriate function …
- 229 views
- 08 Aug, 2021
- 1 location
Screening Microorganism of Cryptogenic Mechanical Pneumonia Through Next Generation Sequencing to Lung Tissue Fluid
The etiology of cryptogenic organizing pneumonia (COP)was not clear, but previous studies have shown that in some patients, some pathogen could be detected in bronchoalveolar lavage fluid (BALF
- 0 views
- 25 Jan, 2021
- 2 locations
A Single-cell Approach to Identify Biomarkers of Pulmonary Toxicity for Immune Checkpoint Blockade
The main goal of this prospective non-interventional exploratory monocentric study is to characterize the immune cell composition of bronchoalveolar lavage (BAL) fluid from cancer patients
- 0 views
- 03 Apr, 2023
- 1 location
Characterization of Pulmonary Langerhans Cell Histiocytosis
mutations in bronchoalveolar lavage will represent a significant advance in the diagnosis and treatment of these patients. An undetermined percentage of HCL does not present mutations in B-RAF. Consequently
- 12 views
- 25 Jan, 2021
- 1 location
Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes
bronchoalveolar lavage fluid (BALF) which may help differentiate the ARDS endotypes.
- 0 views
- 04 Oct, 2022
- 2 locations
A Single-cell Approach to Identify Biomarkers of Efficacy and Toxicity for ICI in NSCLC
of bronchoalveolar lavage (BAL) fluid from these ICI-treated cancer patients if they would develop ICI-pneumonitis. These mechanistic insights can directly lead to putative diagnostic biomarkers and
- 0 views
- 10 Apr, 2023
- 1 location
VOC in Breath Samples for the Diagnosis of IPA
immunosuppressed patient, such as patients with acute myeloid leukemia (AML), relied heavily on chest computed tomography (CT) and bronchoalveolar lavage (BAL), an invasive approach bearing many caveats. Volatile
- 0 views
- 13 Aug, 2023
- 1 location
Exhaled Breath Particles in Lung Cancer
lining fluid (RTLF) and that biomarkers found in EBP correlate to proteins that can be found in both bronchoalveolar lavage fluid (BALF) and plasma. Particle flow rate (PFR) has been found to differ
- 0 views
- 03 Jun, 2022
- 1 location
Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS)
COVID19-induced ARDS. The investigators will also collect EBPs onto a membrane for subsequent molecular analysis. Previous studies have shown that most of those proteins found in bronchoalveolar lavage
- 4 views
- 22 Apr, 2022
- 1 location
Host Response to Infection and Treatment in Filarial Diseases
bronchoalveolar lavage. For this procedure, the mouth and throat are numbed with lidocaine jelly and spray and, if needed, a sedative is given for comfort. A small plastic tube is placed in a vein to give
- 72 views
- 17 Sep, 2023
- 1 location