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Found 79 clinical trials
Treatment of Pneumocystitis in COPD (the TOPIC Study)

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease associated with chronic inflammation in the airways and lung, resulting in significant morbidity and mortality worldwide. Smoking is the primary risk factor for development of COPD and progression of the disease is associated with acute exacerbations of COPD (AECOPD) that …

  • 0 views
  • 09 Jul, 2022
  • 1 location
GSNOR Phenotyping/GSNO Challenge in Severe Asthma

Asthma is caused by or worsened by different things in different people. It is because of these differences that not all people with asthma respond the same to all treatments and medicines. If the investigators can better identify the changes in the airways or breathing pipes in patients with asthma, …

atopy
bronchodilator
pulmonary disease
methacholine
COPD
  • 176 views
  • 16 Mar, 2022
  • 2 locations
Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units (Pop-PK/PD)

Antibiotics are still most often administered on an empiric fashion, as defined for the general population with dosages only adapted based on weight and renal and/or hepatic functions. As a result, serum concentrations show important interpatient variations with the risk of being subtherapeutic or toxic. Recent studies with temocillin, ceftriaxone, …

renal function
pulmonary infection
antibiotics
antibiotic therapy
ceftriaxone
  • 30 views
  • 04 Jun, 2022
  • 1 location
Lung Microbiota Analysis in Critically Ill Patients Admitted to the Intensive Care Unit.

(ICU). In patients undergoing invasive mechanical ventilation, an aliquot of bronchoalveolar lavage (BAL) fluid will be used in the microbiology laboratory for the analysis of respiratory microbiota

  • 0 views
  • 07 Apr, 2022
  • 1 location
Clinical Evaluation of FilmArray LRTI Panel

least 3 study sites of sputum and bronchoalveolar lavage (BAL) specimens that are left over as excess from routine clinical care. Additionally, the study will collect residual whole blood or blood

  • 142 views
  • 08 Nov, 2020
  • 1 location
Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage From Patients With Lung Infiltrates

. Patients will undergo bronchoscopy and bronchoalveolar lavage as scheduled for their medical care. For this procedure, the patient's mouth and throat are numbed with lidocaine; a sedative may be given for

pneumonia
x-rays
bronchoscopy
sedative
withdrawn
  • 29 views
  • 22 Sep, 2022
  • 1 location
Virologic and Immunologic Evaluation of Lymph Node, Tonsillar and Intestinal Biopsies, and Bronchoalveolar Lavage Fluid

tube are used to extract small tissue samples. Bronchoalveolar lavage (BAL; patients and volunteers) Volunteers and patients will undergo bronchoscopy in which a flexible tube (bronchoscope

AIDS
immunosuppressant
HIV Infection
electrocardiogram
Accepts healthy volunteers
  • 252 views
  • 16 Sep, 2022
  • 1 location
Xpert MTB/RIF Ultra Assay for the Detection of Mycobacterium Tuberculosis (MTB) in Bronchoalveolar Lavage (BAL) for Pulmonary TB and Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS-TBNA) Samples for Mediastinal TB (TRiBE)

This prospective observational multi-centre UK study will evaluate Xpert MTB/RIF Ultra for the detection of Mycobacterium tuberculosis (MTB) in bronchoalveolar lavage (BAL) samples for pulmonary

  • 0 views
  • 18 Sep, 2022
  • 1 location
Epidemiologic Clinical Molecular Characteristics of Hospital Employees With or Without Covid-19 Infection

research use of blood, pharyngeal swab, and for those hospitalized for COVID-19, also for the bronchoalveolar lavage and fecal samples. Biological samples will be used to perform cellular, microbial and

covid-19
  • 0 views
  • 24 Jan, 2021
  • 1 location
Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

, cerebrospinal fluid, bronchoalveolar lavage fluid) sample log-in, processing, relabeling, and storage is performed by the Masonic Cancer Center (MCC) Translational Therapy Lab (TTL).

  • 7 views
  • 24 Mar, 2022
  • 1 location