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Found 95 clinical trials
Asthma Sample Collection Protocol

(bronchoalveolar lavage) collects cells. In this study, researchers plan to perform these tests on patients with asthma and normal volunteers. This research may help to improve the understanding of the

  • 23 Nov, 2020
  • 1 location
Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinosis (aPAP)

160 subjects with autoimmune pulmonary alveolar proteinosis (aPAP) will be randomized to receive once daily treatment with inhaled molgramostim or placebo for 48 weeks. Subjects completing the 48 week placebo-controlled period will receive open-label treatment with once daily inhaled molgramostim for 48 weeks.

  • 22 Sep, 2021
  • 40 locations
Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia

This is a multicenter, multinational, open label single dose pharmacokinetic (PK) study enrolling at least 32 subjects. The study aims to characterize the pharmacokinetics (PK) of a single intravenous dose of CAZ AVI in pediatric subjects aged 3 months to less than 18 years who are receiving systemic antibiotic therapy …

  • 02 Jul, 2021
  • 59 locations
Effects of Bronchial Segmental Endotoxin Instillation in Humans

drawn from an arm vein. They will have an intravenous catheter (small plastic tube) placed in a vein. All participants will have bronchoscopy with bronchoalveolar lavage. They will be numbed

  • 22 Sep, 2021
  • 1 location
Contribution of Hypnotic Analgesia to Local Anesthesia During Bronchial Endoscopy.

sampling techniques are bronchoalveolar lavage and endobronchial biopsies. Two steps in the process can be unpleasant for the patient: the crossing of the nasopharynx because of the narrow

  • 26 Jan, 2021
  • 1 location
Prospective Trial of Rituximab for Primary Pulmonary Alveolar Proteinosis

The purpose of this study is to determine whether the use of rituximab is effective in treating pulmonary alveolar proteinosis by leading to an improvement in lung function and disease status.

  • 07 Nov, 2020
  • 1 location
Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study)

The investigators aim to assess the safety and efficacy of nebulized liposomal amphotericin B (ALN) as a complementary therapy to the usual systemic treatment in patients with invasive pulmonary aspergillosis and the utility of a non-routine test as a surrogate marker of efficacy. To this end, a 3-year phase I, …

  • 13 Feb, 2021
  • 1 location
MICRA - Pilot Study

Acute cell rejection is a common complication of lung transplantation. The pathological diagnosis is based on the performance of transbronchial biopsies which are associated with a significant risk of potentially severe pneumothorax and hemoptysis. Confocal microscopy performed during bronchial endoscopy provides real-time images of the lungs on a microscopic scale. …

  • 23 Mar, 2021
  • 1 location
Effect of E-BAL on Severity of VAP Assessed Through CPIS on the Patients of Traumatic Brain Injury in Neurocritical Care Also Effect on Days of Ventilation and ICU Stay.

infection score (CPIS). CPIS is considered as an important clinical indicator of pneumonia in NCCU. Bronchoalveolar Lavage (BAL) is a minimally invasive procedure done with instillation of normal

mechanical ventilation
traumatic brain injury
severe traumatic brain injury
pulmonary infection
  • 06 Aug, 2021
  • 1 location
Pathogens Responsible for Respiratory Infections Associated With Drowning in Seawater

overall management. Carrying out a bronchoalveolar lavage (BAL) within 24 hours after admission to intensive care with analysis on standard and specific culture media of environmental germs

  • 01 Aug, 2021
  • 2 locations