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Found 24 clinical trials
Surgical Weight Loss and Alcohol Perception

absorption by the gastrointestinal tract. Thus, compared to oral ingestion, infusion can achieve the same blood alcohol concentration (BAC) with substantially less total alcohol dosage. Following the

gastric bypass
bypass surgery
  • 27 Jan, 2021
  • 1 location
The College Alcohol and Peers Study (CAPS)

The present study will evaluate college students (N=100) from 2- and 4-year colleges/universities between 21-24 years old to assess anxiety, affect, broad social motives (BSM) and peer group influences on drinking and other risk-taking behaviors. This study will employ two sound scientific methods for testing behavior during drinking events (i.e., …

  • 25 Jan, 2021
  • 1 location
Effect of Citrate Dialysis on Vascular Calcification

The goal of this study is to determine whether hemodialysis with citrate slows the progression of vascular calcification. Participants will be dialyzed with one of two standard dialysis solutions, one with and one without citrate, for 12 months and then switched to the other solution for 12 months. Vascular calcification …

  • 17 Jul, 2021
  • 4 locations
Mavoglurant in Alcohol Drinking

The purpose of this alcohol-interaction pilot study is to provide information on the effect of mavoglurant on the pharmacokinetics of alcohol and on alcohol responses, including stimulation, sedation, intoxication, body sway and physiological responses. The investigators propose to test the effects of 200 mg mavoglurant versus placebo on alcohol related …

  • 22 Jun, 2021
  • 1 location
Measuring Fluid Flow in the Brain Using Alcohol and MRI in Healthy Participants

Intracranial interstitial fluid (ISF) flow is crucial for adequate clearance of extracellular waste products from the brain parenchyma. Recent demonstrations have shown that a deficiency in flow leads to the accumulation of such waste products in neurodegenerative disorders. Unfortunately, no clinical investigation that gives a quantitative measure of ISF flow …

  • 26 Jan, 2021
  • 1 location
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

lung Bronchoalveolar carcinoma lung. This condition is now also referred to as adenocarcinoma in situ, minimally invasive adenocarcinoma, lepidic predominant adenocarcinoma, or invasive

gilbert's syndrome
pancreatic adenocarcinoma
serous adenocarcinoma
absolute neutrophil count
  • 24 Sep, 2021
  • 818 locations
Positron Emission Tomography (PET)/Computed Tomography (CT) and Roentgen in Lung Cancer: Evaluation of Patients in General Practice

The prognosis of lung cancer depends much on the stage of the disease at the time of diagnosis. Only 16 % of lung cancer can be offered curative intended surgery. Chest x-ray is the gate-keeper in lung cancer diagnosis, but it has a miss rate of 20-60 %. A false …

ct scan
  • 07 Nov, 2020
  • 2 locations
First-Line EGFR-1 Tyrosine Kinase Inhibition in Patients With NSCLC With Mutant EGFR Gene

Current chemotherapy for advanced non-small cell lung cancer, not amenable for curative local treatment (surgery or chemoradiotherapy), has a modest life-prolonging effect and can improve quality of life. There is however no potential for long-term cure for these patients. Chemotherapy also produces variable and often significant toxicity. Current retrospective evidence …

kidney function test
renal function
adjuvant chemotherapy
  • 07 Nov, 2020
  • 1 location
Effect of Benzalkonium Chloride Containing Eye Drops on the Conjunctival Bacterial Flora of Dry Eye Patients

Benzalkonium chloride (BAC) is a preservative, which is a component of more than 70% of topical ophthalmic drugs. Although BAC is a preservative with an excellent antibacterial spectrum, it has

  • 18 Sep, 2021
  • 1 location
  • 02 Feb, 2021
  • 1 location