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Found 82 clinical trials
Automation Oxygen Flow Titration in Spontaneously Breathing Infants

The objective of this study is to assess the efficacy of the FreeO2 device in shortening the hospital length of stay during a first episode of hypoxemic bronchiolitis in infants less than 1 year of age. FreeO2Bronchio study is a multicenter, prospective, controlled, randomized, open-label study.

  • 3 views
  • 29 Jul, 2022
  • 7 locations
High Flow Nasal Cannula (HFNC) Initiation Flow Rate Study

The investigators propose an open label, non-blinded, single center randomized controlled feasibility study to find the optimal initial HFNC flow rate in children less than 12 months old with clinically diagnosed moderate to severe bronchiolitis. This feasibility study is projected over December 2020 to April 2023. The study is consisted …

  • 0 views
  • 10 Jul, 2022
  • 1 location
High Flow Nasal Cannula Therapy in Bronchiolitis : Early vs Rescue

The enrolled RSV-bronchiolitis patients will be randomized into two arms , the early HHHFNC group and the standard therapy group with rescue HHHFNC to study the efficacy of this treatment.

  • 3 views
  • 27 Feb, 2022
  • 1 location
Nasal Suction in Infants With Bronchiolitis Using a NoseFrida vs. Bulb Syringe

This research study will evaluate the difference in effectiveness of nasal suction between two different suction devices (NoseFrida and bulb syringe) in infants that have bronchiolitis. Bronchiolitis (a virus infection that goes into the lungs, which subsequently causes difficulty breathing, difficulty sleeping, and difficulty eating and drinking in children) is …

cough
fever
  • 0 views
  • 23 Mar, 2022
  • 1 location
RheOx Registry Study in Europe

Post-market clinical study (registry study) to collect post-market safety and clinical utility data in European patients with chronic bronchitis treated with RheOx.

bronchitis
  • 3 views
  • 13 Apr, 2022
  • 2 locations
Effect of Losartan on Chronic Obstructive Pulmonary Disease (COPD)

Losartan, an angiotensin receptor blocker, has been effective in preventing the development of emphysema and lung inflammation in animal models of COPD. Moreover, there is epidemiologic evidence that suggests that this drug may be effective in reducing COPD morbidity and mortality. This study will provide treatment with either losartan or …

emphysema
losartan
pulmonary disease
COPD
  • 857 views
  • 07 Nov, 2020
  • 1 location
Energy Supply in Athletes and Untrained Persons With Bronchopulmonary Diseases

Study of the energy supply of bicycle ergometric load in athletes and untrained persons with bronchopulmonary diseases (community-acquired pneumonia, bronchitis, chronic obstructive pulmonary

respiratory infection
bronchitis
bronchopulmonary diseases
pulmonary disease
respiratory viral infection
  • 0 views
  • 24 Jan, 2021
  • 1 location
HHHFA in COPD Patients, With Chronic Bronchitis

Heated, humidified high-flow air (HHHFA) devices improve airway clearance. HHHFA use for an average of 1.6 hours a day in COPD patients with chronic bronchitis improves health-related quality of

  • 0 views
  • 03 Jun, 2022
  • 1 location
The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor

The study is a Phase 2 Study to establish the safety and efficacy of a drug called Ivacaftor (VX-770) in patients with chronic obstructive pulmonary disease (COPD), chronic bronchitis, and

bronchitis
copd exacerbation
pulmonary disease
diabetes
sweat chloride
  • 140 views
  • 09 Apr, 2022
  • 1 location
Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis (PLATyPuS)

Plastic bronchitis (PB) is a rare, most often pediatric disease characterized by the formation of obstructive airway casts primarily composed of fibrin. There is presently no FDA-approved

Accepts healthy volunteers
  • 54 views
  • 19 Jun, 2022
  • 2 locations