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Found 81 clinical trials
Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis (RheSolve)

effectiveness of Bronchial Rheoplasty for the treatment of the symptoms of chronic bronchitis in adult COPD patients with moderate to severe chronic bronchitis. A total of 270 patients will be randomized at up

bronchodilator
COPD
cigarette smoke
cough
  • 7 views
  • 23 Jul, 2022
  • 13 locations
High Flow Nasal Cannula in Pediatric Patients After Cardiothoracic Surgery (OSACA CATS)

infants who suffer from bronchitis. However there is no evidence showing that HFNC can reduce "treatment failure" after extubation in pediatric patients after cardiothoracic surgery. This

  • 0 views
  • 08 Jul, 2022
  • 1 location
Woodsmoke Particulate + Prednisone (Smokisone)

Deployment of military personnel has been associated with increased respiratory illness likely due, in part, to inhalation of unusual particulate matter (PM), such as from burn pits. Inflammation is a key initial response to inhaled particulates. The researchers have developed a protocol using inhaled wood smoke particles (WSP) as a …

Accepts healthy volunteers
  • 0 views
  • 08 Aug, 2022
  • 1 location
  • 96 views
  • 09 Aug, 2022
  • 91 locations
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

A multi-center, randomized, 36-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at …

pulmonary disease
azithromycin
corticosteroids
COPD
muscarinic antagonist
  • 265 views
  • 11 Apr, 2022
  • 30 locations
Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children (SIP)

This study's objective is to identify and test pragmatic and sustainable strategies for implementing a multi-condition clinical pathway intervention for children hospitalized with asthma, pneumonia, or bronchiolitis in community hospitals. The hypothesis is that the multi-condition pathway intervention will be associated with significantly greater increases in clinicians' adoption of evidence-based …

asthma
pneumonia
  • 0 views
  • 09 Jun, 2022
  • 1 location
A 52-week Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)

The purpose of the study is to evaluate the efficacy and safety of two doses of CHF6001 (Tanimilast), as add-on to maintenance triple therapy in the target patient population.

  • 0 views
  • 12 Aug, 2021
  • 1 location
A 52-week Placebo- and Active- Controlled (Roflumilast Daliresp 500 g) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)

The purpose of this study is to evaluate the efficacy and the safety of two doses of CHF6001 (Tanimilast) as add-on to maintenance triple therapy in the target patient population.

  • 0 views
  • 11 Aug, 2021
  • 1 location
Improving Antibiotic Use in Urgent Care Facilities (SCORE_UC)

This study will implement a comprehensive outpatient stewardship program targeting a large network of Urgent Care (UC) clinics within Intermountain Helathcare.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
Suctioning of NOse Therapy in Bronchiolitis (SNOT)

Research Questions: Primary In otherwise healthy infants 4 weeks to 12 months of age discharged home from the ED with acute bronchiolitis,1 is there a difference in the probability of "treatment failure" by 72 hours post discharge from the index ED visit in those receiving nasal suctioning via Zo-Li device …

asthma
acute bronchiolitis
respiratory distress
  • 0 views
  • 17 Jun, 2022
  • 1 location